Studies of drug-excipient compatibility represent an important phase in the pre-formulation
stage for the development of all dosage forms. The potential physical and chemical …

Thermogravimetry/derivative thermogravimetry (TG/DTG) and differential scanning
calorimetry (DSC) techniques were used for assessing the compatibility between ketoprofen …

Abstract Posaconazole (PSZ), an anti-fungal drug, has broad-spectrum activity. But its action
is limited due to the poor solubility of posaconazole. The objective of the present study was …

Over the past few decades, the amorphous solid dispersions (ASDs) technique has
emerged as a promising strategy to enhance the in vitro/in vivo characteristic of hydrophobic …

Ketoconazole (KTZ) is an antifungal agent responsible for the inhibition of 14-α-demethylase
sterol. The drug–excipient compatibility studies play an important role in pharmaceutical …

The aim of this study was to characterize atorvastatin and evaluate interactions between
atorvastatin and various excipients by DSC and FTIR, using Pearson's correlation as a tool …

First-line drugs (rifampicin, RIF; isoniazid, INH; ethambutol, ETA; and pyrazinamide, PZA)
recommended in conventional treatment of tuberculosis were analyzed in 1: 1 w/w binary …

Nanocarriers may provide interesting delivery platforms for microbicide drugs and their
characterization should be addressed early in development. Differently surface-engineered …

Abstract Purpose 5-Chloro-3-[phenylsulfonyl] indole-2-carboxamide (CSIC) is a highly
potent non-nucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1 which has been …

The biowaiver of bioequivalence studies on class I drugs of the biopharmaceutics
classification system (BCS) is aimed mainly at reducing the costs and the exposure of health …