Lipids play crucial roles in signal transduction, contribute to the structural integrity of cellular
membranes, and regulate energy metabolism. Questions remain as to which lipid species …

As the principal tissue for insulin-stimulated glucose disposal, skeletal muscle is a primary
driver of whole-body glycemic control. Skeletal muscle also uniquely responds to muscle …

The insulin receptor (IR) is a type II receptor tyrosine kinase that plays essential roles in
metabolism, growth, and proliferation. Dysregulation of IR signaling is linked to many human …

A healthy adipose tissue (AT) is indispensable to human wellbeing. Among other roles, it
contributes to energy homeostasis and provides insulation for internal organs. Adipocytes …

Aedes aegypti female mosquitoes require vertebrate blood for their egg production and
consequently they become vectors of devastating human diseases. Amino acids (AAs) and …

Background The discovery of insulin in 1921 and its near-immediate clinical use initiated a
century of innovation. Advances extended across a broad front, from the stabilization of …

(1) Background: studies on the long-term dynamic changes in fat depot metabolism in
response to a high-fat diet (HFD) on hepatic lipid deposition and insulin resistance are …

Dyslipidemia and autophagy have been implicated in the pathogenesis of blinding
neovascular age-related macular degeneration (NV-AMD). VLDL receptor (VLDLR) …

Patients suffering from musculoskeletal diseases must cope with a diminished quality of life
and an increased burden on medical expenses. The interaction of immune cells and …

Abstract Background and Aims Sleeve gastrectomy (VSG) leads to improvement in hepatic
steatosis, associated with weight loss. The aims of this study were to investigate whether …