Studying microplastics: Lessons from evaluated literature on animal model organisms and experimental approaches

MD Prokić, BR Gavrilović, TB Radovanović… - Journal of Hazardous …, 2021 - Elsevier
Although we are witnesses of an increase in the number of studies examining the
exposure/effects of microplastics (MPs) on different organisms, there are many unknowns …

Considering aspects of the 3Rs principles within experimental animal biology

LU Sneddon, LG Halsey… - Journal of Experimental …, 2017 - journals.biologists.com
ABSTRACT The 3Rs–Replacement, Reduction and Refinement–are embedded into the
legislation and guidelines governing the ethics of animal use in experiments. Here, we …

[HTML][HTML] Adverse effects in the fish embryo acute toxicity (FET) test: a catalogue of unspecific morphological changes versus more specific effects in zebrafish (Danio …

R von Hellfeld, K Brotzmann, L Baumann… - Environmental Sciences …, 2020 - Springer
Abstract Background The Fish Embryo Acute Toxicity (FET) test with the zebrafish (Danio
rerio) embryo, the OECD test guideline (TG) 236, has been designed as an alternative for …

Applicability of the fish embryo acute toxicity (FET) test (OECD 236) in the regulatory context of Registration, Evaluation, Authorisation, and Restriction of Chemicals …

M Sobanska, S Scholz, AM Nyman… - Environmental …, 2018 - Wiley Online Library
Abstract In 2013 the Organisation for Economic Co‐operation and Development (OECD) test
guideline (236) for fish embryo acute toxicity (FET) was adopted. It determines the acute …

[HTML][HTML] Development of AOP relevant to microplastics based on toxicity mechanisms of chemical additives using ToxCast™ and deep learning models combined …

J Jeong, J Choi - Environment international, 2020 - Elsevier
Various additives are used in plastic products to improve the properties and the durability of
the plastics. Their possible elution from the plastics when plastics are fragmented into micro …

A test battery for assessing the ecotoxic effects of textile dyes

GAR de Oliveira, DM Leme, J de Lapuente… - Chemico-biological …, 2018 - Elsevier
The textile dyeing industry is one of the main sectors contributing to environmental pollution,
due to the generation of large amounts of wastewater loaded with dyes (ca. 2–50% of the …

[HTML][HTML] Hypo-or hyperactivity of zebrafish embryos provoked by neuroactive substances: a review on how experimental parameters impact the predictability of …

A Ogungbemi, D Leuthold, S Scholz… - Environmental Sciences …, 2019 - Springer
Tests with zebrafish embryos have gained wide acceptance as an alternative test model for
drug development and toxicity testing. In particular, the behavioral response of the zebrafish …

The potential connections of adverse outcome pathways with the hazard identifications of typical organophosphate esters based on toxicity mechanisms

Z Yan, X Jin, D Liu, Y Hong, W Liao, C Feng, Y Bai - Chemosphere, 2021 - Elsevier
Following the world-wide ban of brominated flame retardants (BFRs), organophosphate
esters (OPEs), which could potentially affect human health and ecosystem safety, have been …

Enzymatic biotesting: scientific basis and application

EN Esimbekova, IG Torgashina, VP Kalyabina… - … problems of ecology, 2021 - Springer
The paper provides a review of the current state of research in the field of biotesting, and the
problems of environmental studies and ways to solve them are discussed. The basic …

Challenges in the interpretation of anticoagulant rodenticide residues and toxicity in predatory and scavenging birds

BA Rattner, JJ Harvey - Pest Management Science, 2021 - Wiley Online Library
Anticoagulant rodenticides (ARs) are part of the near billion‐dollar rodenticide industry.
Numerous studies have documented the presence of ARs in nontarget wildlife, with …