Absence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca2+, Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy

DG Allen, NP Whitehead… - Physiological …, 2016 - journals.physiology.org
Dystrophin is a long rod-shaped protein that connects the subsarcolemmal cytoskeleton to a
complex of proteins in the surface membrane (dystrophin protein complex, DPC), with further …

Brain dystrophin, neurogenetics and mental retardation

MF Mehler - Brain Research Reviews, 2000 - Elsevier
Duchenne muscular dystrophy (DMD) and the allelic disorder Becker muscular dystrophy
(BMD) are common X-linked recessive neuromuscular disorders that are associated with a …

Assembly of the dystrophin-associated protein complex does not require the dystrophin COOH-terminal domain

GE Crawford, JA Faulkner, RH Crosbie… - The Journal of cell …, 2000 - rupress.org
Dystrophin is a multidomain protein that links the actin cytoskeleton to laminin in the
extracellular matrix through the dystrophin associated protein (DAP) complex. The COOH …

Dystrophin Dp71: the smallest but multifunctional product of the Duchenne muscular dystrophy gene

R Tadayoni, A Rendon, LE Soria-Jasso… - Molecular …, 2012 - Springer
Dystrophin Dp71 is expressed in all tissues, with the exception of skeletal muscle, and is the
main Duchenne muscular dystrophy (DMD) gene product in brain. As full-length dystrophin …

Metabolic profiling of genetic disorders: a multitissue 1H nuclear magnetic resonance spectroscopic and pattern recognition study into dystrophic tissue

JL Griffin, HJ Williams, E Sang, K Clarke, C Rae… - Analytical …, 2001 - Elsevier
A principal problem in understanding the functional genomics of a pathology is the wide-
reaching biochemical effects that occur when the expression of a given protein is altered. To …

Expression and synthesis of alternatively spliced variants of Dp71 in adult human brain

RC Austin, GE Morris, PL Howard, HJ Klamut… - Neuromuscular …, 2000 - Elsevier
Transcripts encoding the 70–75 kDa C-terminal protein product of the dystrophin gene
(Dp71) are alternatively spliced to generate multiple protein products in a number of adult …

[HTML][HTML] Marine bisindole alkaloid: A potential apoptotic inducer in human cancer cells

S Salucci, S Burattini, F Buontempo… - European Journal of …, 2018 - ncbi.nlm.nih.gov
Marine organisms such as corals, sponges and tunicates produce active molecules which
could represent a valid starting point for new drug development processes. Among the …

Biochemical and histochemical analysis of 71 kDa dystrophin isoform (Dp71f) in rat brain

C Garcia-Tovar, A Perez, J Luna, R Mena, B Osorio… - Acta …, 2001 - Elsevier
Dp71 is a member of the dystrophin family and the most abundant dmd gene product in the
brain. In the present study, we focused on a short dystrophin transcript named Dp71f, which …

[HTML][HTML] Diagnosis of sudden cardiac death due to early myocardial ischemia: An ultrastructural and immunohistochemical study

SD Visonà, D Benati, MC Monti, M Galiè… - European Journal of …, 2018 - ncbi.nlm.nih.gov
The aim of this post-mortem ultrastructural and immunohistochemical study is to explore the
characteristics of acute myocardial ischemia in the context of sudden death, using the …

[HTML][HTML] Distribution of non-myelinating Schwann cells and their associations with leukocytes in mouse spleen revealed by immunofluorescence staining

B Ma, C Yin, D Hu, M Newman… - European Journal of …, 2018 - ncbi.nlm.nih.gov
The nervous system and the immune system communicate extensively with each other in
order to maintain homeostasis and to regulate the immune response. The peripheral …