Extracellular vesicles: A bright star of nanomedicine
P Wu, B Zhang, DKW Ocansey, W Xu, H Qian - Biomaterials, 2021 - Elsevier
Extracellular vesicles (EVs) have unique structural, compositional, and morphological
characteristics as well as predominant physiochemical stability and biocompatibility …
characteristics as well as predominant physiochemical stability and biocompatibility …
Current challenges and future directions for engineering extracellular vesicles for heart, lung, blood and sleep diseases
Extracellular vesicles (EVs) carry diverse bioactive components including nucleic acids,
proteins, lipids and metabolites that play versatile roles in intercellular and interorgan …
proteins, lipids and metabolites that play versatile roles in intercellular and interorgan …
[HTML][HTML] Evolution of blood–brain barrier in brain diseases and related systemic nanoscale brain-targeting drug delivery strategies
L Han, C Jiang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Blood–brain barrier (BBB) strictly controls matter exchange between blood and brain, and
severely limits brain penetration of systemically administered drugs, resulting in ineffective …
severely limits brain penetration of systemically administered drugs, resulting in ineffective …
[HTML][HTML] Therapeutic potential of exosome‐based personalized delivery platform in chronic inflammatory diseases
C Wang, M Xu, Q Fan, C Li, X Zhou - Asian journal of pharmaceutical …, 2023 - Elsevier
In the inflammatory microenvironment, there are numerous exosomes secreted by immune
cells (Macrophages, neutrophils, dendritic cells), mesenchymal stem cells (MSCs) and …
cells (Macrophages, neutrophils, dendritic cells), mesenchymal stem cells (MSCs) and …
[HTML][HTML] Advances in extracellular vesicle functionalization strategies for tissue regeneration
Extracellular vesicles (EVs) are nano-scale vesicles derived by cell secretion with unique
advantages such as promoting cell proliferation, anti-inflammation, promoting blood vessels …
advantages such as promoting cell proliferation, anti-inflammation, promoting blood vessels …
Present and future of bronchopulmonary dysplasia
L Bonadies, P Zaramella, A Porzionato… - Journal of clinical …, 2020 - mdpi.com
Bronchopulmonary dysplasia (BPD) is the most common respiratory disorder among infants
born extremely preterm. The pathogenesis of BPD involves multiple prenatal and postnatal …
born extremely preterm. The pathogenesis of BPD involves multiple prenatal and postnatal …
[HTML][HTML] Extracellular vesicle-based Nanotherapeutics: Emerging frontiers in anti-inflammatory therapy
TT Tang, B Wang, LL Lv, BC Liu - Theranostics, 2020 - ncbi.nlm.nih.gov
Dysregulated inflammation is a complicated pathological process involved in various
diseases, and the treatment of inflammation-linked disorders currently represents an …
diseases, and the treatment of inflammation-linked disorders currently represents an …
Neutrophils and macrophages as targets for development of nanotherapeutics in inflammatory diseases
Neutrophils and macrophages are major components of innate systems, playing central
roles in inflammation responses to infections and tissue injury. If they are out of control …
roles in inflammation responses to infections and tissue injury. If they are out of control …
Extracellular vesicles as antigen carriers for novel vaccination avenues
Antigen delivery has always been a challenge in scientific practice of vaccine formulation.
Yet, mammalian extracellular vesicles (EVs) or bacterial membrane vesicles (MVs) provide …
Yet, mammalian extracellular vesicles (EVs) or bacterial membrane vesicles (MVs) provide …
The functional heterogeneity of neutrophil-derived extracellular vesicles reflects the status of the parent cell
Similar to other cell types, neutrophilic granulocytes also release extracellular vesicles
(EVs), mainly medium-sized microvesicles/microparticles. According to published data …
(EVs), mainly medium-sized microvesicles/microparticles. According to published data …