Extracellular vesicles: A bright star of nanomedicine

P Wu, B Zhang, DKW Ocansey, W Xu, H Qian - Biomaterials, 2021 - Elsevier
Extracellular vesicles (EVs) have unique structural, compositional, and morphological
characteristics as well as predominant physiochemical stability and biocompatibility …

Current challenges and future directions for engineering extracellular vesicles for heart, lung, blood and sleep diseases

G Li, T Chen, J Dahlman… - Journal of …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) carry diverse bioactive components including nucleic acids,
proteins, lipids and metabolites that play versatile roles in intercellular and interorgan …

[HTML][HTML] Evolution of blood–brain barrier in brain diseases and related systemic nanoscale brain-targeting drug delivery strategies

L Han, C Jiang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Blood–brain barrier (BBB) strictly controls matter exchange between blood and brain, and
severely limits brain penetration of systemically administered drugs, resulting in ineffective …

[HTML][HTML] Therapeutic potential of exosome‐based personalized delivery platform in chronic inflammatory diseases

C Wang, M Xu, Q Fan, C Li, X Zhou - Asian journal of pharmaceutical …, 2023 - Elsevier
In the inflammatory microenvironment, there are numerous exosomes secreted by immune
cells (Macrophages, neutrophils, dendritic cells), mesenchymal stem cells (MSCs) and …

[HTML][HTML] Advances in extracellular vesicle functionalization strategies for tissue regeneration

D Zheng, H Ruan, W Chen, Y Zhang, W Cui, H Chen… - Bioactive Materials, 2023 - Elsevier
Extracellular vesicles (EVs) are nano-scale vesicles derived by cell secretion with unique
advantages such as promoting cell proliferation, anti-inflammation, promoting blood vessels …

Present and future of bronchopulmonary dysplasia

L Bonadies, P Zaramella, A Porzionato… - Journal of clinical …, 2020 - mdpi.com
Bronchopulmonary dysplasia (BPD) is the most common respiratory disorder among infants
born extremely preterm. The pathogenesis of BPD involves multiple prenatal and postnatal …

[HTML][HTML] Extracellular vesicle-based Nanotherapeutics: Emerging frontiers in anti-inflammatory therapy

TT Tang, B Wang, LL Lv, BC Liu - Theranostics, 2020 - ncbi.nlm.nih.gov
Dysregulated inflammation is a complicated pathological process involved in various
diseases, and the treatment of inflammation-linked disorders currently represents an …

Neutrophils and macrophages as targets for development of nanotherapeutics in inflammatory diseases

Y Su, J Gao, P Kaur, Z Wang - Pharmaceutics, 2020 - mdpi.com
Neutrophils and macrophages are major components of innate systems, playing central
roles in inflammation responses to infections and tissue injury. If they are out of control …

Extracellular vesicles as antigen carriers for novel vaccination avenues

M Mehanny, CM Lehr, G Fuhrmann - Advanced drug delivery reviews, 2021 - Elsevier
Antigen delivery has always been a challenge in scientific practice of vaccine formulation.
Yet, mammalian extracellular vesicles (EVs) or bacterial membrane vesicles (MVs) provide …

The functional heterogeneity of neutrophil-derived extracellular vesicles reflects the status of the parent cell

F Kolonics, V Szeifert, CI Timár, E Ligeti, ÁM Lőrincz - Cells, 2020 - mdpi.com
Similar to other cell types, neutrophilic granulocytes also release extracellular vesicles
(EVs), mainly medium-sized microvesicles/microparticles. According to published data …