[HTML][HTML] Cryptococcus escapes host immunity: What do we know?

C Yang, Y Huang, Y Zhou, X Zang, H Deng… - Frontiers in Cellular …, 2022 - frontiersin.org
Cryptococcus is an invasive fungus that seriously endangers human life and health, with a
complex and well-established immune-escaping mechanism that interferes with the function …

[HTML][HTML] TcpC inhibits M1 but promotes M2 macrophage polarization via regulation of the MAPK/NF-κB and Akt/STAT6 pathways in urinary tract infection

J Fang, Q Ou, B Wu, S Li, M Wu, J Qiu, N Cen, K Hu… - Cells, 2022 - mdpi.com
TcpC is a multifunctional virulence factor of Uropathogenic Escherichia coli (UPEC).
Macrophages can differentiate into two different subsets M1 and M2 that play distinct roles in …

[HTML][HTML] Adaptive immunology of Cryptococcus neoformans infections—an update

J Chen, J Shao, M Dai, W Fang, Y Yang - Frontiers in immunology, 2023 - frontiersin.org
The fungal genus Cryptococcus comprises a group of pathogens with considerable
phenotypic and genotypic diversity that can lead to cryptococcosis in both healthy and …

[HTML][HTML] Cryptococcal immune reconstitution inflammatory syndrome: from clinical studies to animal experiments

ZW Shi, Y Chen, KM Ogoke, AB Strickland, M Shi - Microorganisms, 2022 - mdpi.com
Cryptococcus neoformans is an encapsulated pathogenic fungus that initially infects the
lung but can migrate to the central nervous system (CNS), resulting in meningoencephalitis …

Antifungal Peptide SP1 Damages Polysaccharide Capsule of Cryptococcus neoformans and Enhances Phagocytosis of Macrophages

Y Liu, Y Zhang, X Zhao, W Lu, Y Zhong… - Microbiology …, 2023 - Am Soc Microbiol
Cryptococcus neoformans is a fungal pathogen which causes nearly half a million deaths
worldwide each year. Under host-relevant conditions, it produces a characteristic …

Arginase 1 expression by macrophages promotes Cryptococcus neoformans proliferation and invasion into brain microvascular endothelial cells

A Hansakon, C Ngamphiw, S Tongsima… - The Journal of …, 2023 - journals.aai.org
Cryptococcal meningoencephalitis caused by Cryptococcus neoformans infection is the
most common cause of death in HIV/AIDS patients. Macrophages are pivotal for the …

Antifungal and antibiofilm effect of duloxetine hydrochloride against Cryptococcus neoformans and Cryptococcus gattii

AR Rehem, LR da Gama Viveiro… - Folia Microbiologica, 2024 - Springer
Cryptococcosis is an invasive mycosis caused mainly by Cryptococcus gattii and C.
neoformans and is treated with amphotericin B (AMB), fluconazole and 5-fluorocytosine …

[HTML][HTML] Neglected mycobiome in HIV infection: Alterations, common fungal diseases and antifungal immunity

S Li, X Yang, C Moog, H Wu, B Su, T Zhang - Frontiers in Immunology, 2022 - frontiersin.org
Human immunodeficiency virus (HIV) infection might have effects on both the human
bacteriome and mycobiome. Although many studies have focused on alteration of the …

Macrophages-derived exo-miR-4449 induced by Cryptococcus affects HUVEC permeability and promotes pyroptosis in BEAS-2B via the HIC1 pathway

X Li, J Xu, X Lin, Q Lin, T Yu, L Chen, L Chen, X Huang… - Cytokine, 2024 - Elsevier
Macrophages have recently been discovered to assume a significant role in the progression
of cryptococcosis. However, the potential involvement of macrophage-derived exosomes in …

Fungal vaccines and adjuvants: a tool to reveal the interaction between host and fungi

Z Wang, J Shao - Archives of Microbiology, 2024 - Springer
Fungal infections are incurring high risks in a range from superficial mucosal discomforts
(such as oropharyngeal candidiasis and vulvovaginal candidiasis) to disseminated life …