Over the last decade, advances in genetics, neuroimaging and EEG have enabled the
aetiology of epilepsy to be identified earlier in the disease course than ever before. At the …

Children with infantile spasms are likely to have a poor outcome. Outcome measures for
infantile spasms include primary response to treatment, relapse of spasms, neurological …

Despite progress in the development of anti‐seizure medications (ASMs), one third of
people with epilepsy have drug‐resistant epilepsy (DRE). The working definition of DRE …

West syndrome (WS), also known as infantile spasms, occurs in infancy with a peak
between 4 and 7 months. Spasms, neurodevelopmental regression and hypsarrhythmia on …

Background The aims of this systematic review and meta-analysis were to assess (i)
estimates of good neurodevelopmental outcome in infantile spasms (IS),(ii) if …

Epileptic encephalopathies are a group of diseases in which epileptic activity itself
contributes to severe cognitive and behavioral impairments above and beyond what might …

Purpose Delayed diagnosis of early onset epilepsy is a potentially important and avoidable
complication in epilepsy care. We examined the frequency of diagnostic delays in young …

ABSTRACT BACKGROUND No large-scale studies have specifically evaluated the
outcomes of infantile spasms (IS) of unknown cause, previously known as cryptogenic or …

Ketogenic diet (KD) is an efficient treatment for refractory epilepsy including infantile spasms
(IS). We evaluated the effect of a KD to treat IS as a third-line treatment, after vigabatrin …

Objective To determine the association between delays in access to specialist epilepsy care
and patient outcomes. Methods Three databases were searched using eligibility criteria …