Impact of predictive, preventive and precision medicine strategies in epilepsy
R Nabbout, M Kuchenbuch - Nature Reviews Neurology, 2020 - nature.com
Over the last decade, advances in genetics, neuroimaging and EEG have enabled the
aetiology of epilepsy to be identified earlier in the disease course than ever before. At the …
aetiology of epilepsy to be identified earlier in the disease course than ever before. At the …
Infantile spasms: outcome in clinical studies
R Riikonen - Pediatric neurology, 2020 - Elsevier
Children with infantile spasms are likely to have a poor outcome. Outcome measures for
infantile spasms include primary response to treatment, relapse of spasms, neurological …
infantile spasms include primary response to treatment, relapse of spasms, neurological …
Revisiting the concept of drug‐resistant epilepsy: a TASK1 report of the ILAE/AES Joint Translational Task Force
S Auvin, AS Galanopoulou, SL Moshé, H Potschka… - …, 2023 - Wiley Online Library
Despite progress in the development of anti‐seizure medications (ASMs), one third of
people with epilepsy have drug‐resistant epilepsy (DRE). The working definition of DRE …
people with epilepsy have drug‐resistant epilepsy (DRE). The working definition of DRE …
West syndrome: a review and guide for paediatricians
R D'Alonzo, D Rigante, E Mencaroni… - Clinical drug …, 2018 - Springer
West syndrome (WS), also known as infantile spasms, occurs in infancy with a peak
between 4 and 7 months. Spasms, neurodevelopmental regression and hypsarrhythmia on …
between 4 and 7 months. Spasms, neurodevelopmental regression and hypsarrhythmia on …
Neurodevelopmental outcome of infantile spasms: a systematic review and meta-analysis
E Widjaja, C Go, B McCoy, OC Snead - Epilepsy research, 2015 - Elsevier
Background The aims of this systematic review and meta-analysis were to assess (i)
estimates of good neurodevelopmental outcome in infantile spasms (IS),(ii) if …
estimates of good neurodevelopmental outcome in infantile spasms (IS),(ii) if …
Current understanding and neurobiology of epileptic encephalopathies
Epileptic encephalopathies are a group of diseases in which epileptic activity itself
contributes to severe cognitive and behavioral impairments above and beyond what might …
contributes to severe cognitive and behavioral impairments above and beyond what might …
Diagnostic delays in children with early onset epilepsy: impact, reasons, and opportunities to improve care
AT Berg, T Loddenkemper, CB Baca - Epilepsia, 2014 - Wiley Online Library
Purpose Delayed diagnosis of early onset epilepsy is a potentially important and avoidable
complication in epilepsy care. We examined the frequency of diagnostic delays in young …
complication in epilepsy care. We examined the frequency of diagnostic delays in young …
Infantile spasms of unknown cause: predictors of outcome and genotype-phenotype correlation
CJ Yuskaitis, MRZ Ruzhnikov, KB Howell, IE Allen… - Pediatric …, 2018 - Elsevier
ABSTRACT BACKGROUND No large-scale studies have specifically evaluated the
outcomes of infantile spasms (IS) of unknown cause, previously known as cryptogenic or …
outcomes of infantile spasms (IS) of unknown cause, previously known as cryptogenic or …
Ketogenic diet for infantile spasms refractory to first-line treatments: an open prospective study
ME Pires, A Ilea, E Bourel, V Bellavoine, D Merdariu… - Epilepsy research, 2013 - Elsevier
Ketogenic diet (KD) is an efficient treatment for refractory epilepsy including infantile spasms
(IS). We evaluated the effect of a KD to treat IS as a third-line treatment, after vigabatrin …
(IS). We evaluated the effect of a KD to treat IS as a third-line treatment, after vigabatrin …
What is the effect of delays in access to specialist epilepsy care on patient outcomes? A systematic review and meta-analysis
Objective To determine the association between delays in access to specialist epilepsy care
and patient outcomes. Methods Three databases were searched using eligibility criteria …
and patient outcomes. Methods Three databases were searched using eligibility criteria …