The popularity of nanogel as nano drug carrier lies in its adjustable physical properties, and
the ability to encapsulate drug particles with improved properties is being developed to meet …

Fourteen recent thiazolidine-2, 4-diones bearing furan and/or thiophene heterocyclic rings
have been designed, synthesized and assessed for their anticancer activities against four …

Cyclodextrins (CDs) are naturally occurring cyclic oligosaccharides bearing a basket-
shaped topology with an “inner–outer” amphiphilic character. The abundance of hydroxyl …

Abstract Pyrano [2, 3-d] pyrimidine derivatives were synthesized by treating cyclic
compounds containing active methylene group with aldehyde and malononitrile in butanol …

The anticancer activity of novel thiazolidine‐2, 4‐diones was evaluated against HepG2, HCT‐
116, and MCF‐7 cells. MCF‐7 was the most sensitive cell line to the cytotoxicity of the new …

In the designed compounds, a new linker was inserted in the form of fragments with verified
VEGFR‐2 inhibitory potential, including an α, β‐unsaturated ketonic fragment, pyrazole, and …

Targeting PCAF with small inhibitor molecules has emerged as a potential therapeutic
strategy for the treatment of cancer. Recently, L-45 was identified as a potent …

A new series of sulfonamide endowed with hydrazone coupled to dimethyl and/or diethyl
malonates were prepared. Various sulfa drugs were diazotized and followed by coupling …

The discovery of potent STAT3 inhibitors has gained noteworthy impetus in the last decade.
In line with this trend, considering the proven biological importance of 1, 2, 4-triazoles …

Once regarded obscure and underappreciated, the gut microbiota (the microbial
communities colonizing the gastrointestinal tract) is gaining recognition as an influencer of …