Pulmonary surfactant: a mighty thin film

F Possmayer, YY Zuo, RAW Veldhuizen… - Chemical …, 2023 - ACS Publications
Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …

Formulation in Surfactant Systems: From-Winsor-to-HLDN

JL Salager, R Marquez, J Bullon, A Forgiarini - Encyclopedia, 2022 - mdpi.com
Formulation is an ancient concept, although the word has been used only recently. The first
formulations made our civilization advance by inventing bronze, steel, and gunpowder; then …

Pulmonary surfactant in adult ARDS: current perspectives and future directions

A Dushianthan, MPW Grocott, GS Murugan… - Diagnostics, 2023 - mdpi.com
Acute respiratory distress syndrome (ARDS) is a major cause of hypoxemic respiratory
failure in adults, leading to the requirement for mechanical ventilation and poorer outcomes …

A multiplex inhalation platform to model in situ like aerosol delivery in a breathing lung-on-chip

A Sengupta, A Dorn, M Jamshidi, M Schwob… - Frontiers in …, 2023 - frontiersin.org
Prolonged exposure to environmental respirable toxicants can lead to the development and
worsening of severe respiratory diseases such as asthma, chronic obstructive pulmonary …

Role of micellar nanoreactors in organic chemistry: Green and synthetic surfactant review

V Sorhie, B Gogoi, B Walling, SA Acharjee… - Sustainable Chemistry …, 2022 - Elsevier
Over the last few decades surface active compounds in aqueous media have proven to be
the most benign alternative for overcoming the difficulty of insolubility and hydrolytic …

Evolution of interfacial mechanics of lung surfactant mimics progression of acute respiratory distress syndrome

CO Ciutara, SV Iasella, B Huang… - Proceedings of the …, 2023 - National Acad Sciences
How acute respiratory distress syndrome progresses from underlying disease or trauma is
poorly understood, and there are no generally accepted treatments resulting in a 40 …

Surfactant proteins SP-B and SP-C in pulmonary surfactant monolayers: Physical properties controlled by specific protein–lipid interactions

J Liekkinen, A Olzynska, L Cwiklik… - Langmuir, 2023 - ACS Publications
The lining of the alveoli is covered by pulmonary surfactant, a complex mixture of surface-
active lipids and proteins that enables efficient gas exchange between inhaled air and the …

Interfacial dynamics of adsorption layers as supports for biomedical research and diagnostics

E Santini, I Nepita, AG Bykov, F Ravera, L Liggieri… - Colloids and …, 2022 - mdpi.com
The input of chemical and physical sciences to life sciences is increasingly important.
Surface science as a complex multidisciplinary research area provides many relevant …

Bioinspired zwitterionic triblock copolymers designed for colloidal drug delivery: 2-Biological evaluation

M Beck-Broichsitter - Colloids and Surfaces B: Biointerfaces, 2024 - Elsevier
In this work, poly (lactide) nanoparticles were equipped with a bioinspired coating layer
based on poly [2-(methacryloyloxy) ethyl phosphorylcholine] and then evaluated when …

Mitochondrial membrane models built from native lipid extracts: Interfacial and transport properties

O Schiaffarino, D Valdivieso González… - Frontiers in Molecular …, 2022 - frontiersin.org
The mitochondrion is an essential organelle enclosed by two membranes whose
functionalities depend on their very specific protein and lipid compositions. Proteins from the …