Current detection technologies for circulating tumor cells

Z Shen, A Wu, X Chen - Chemical Society Reviews, 2017 - pubs.rsc.org
Circulating tumor cells (CTCs) are cancer cells that circulate in the blood stream after being
naturally shed from original or metastatic tumors, and can lead to a new fatal metastasis …

American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer

L Harris, H Fritsche, R Mennel, L Norton… - Journal of clinical …, 2007 - ascopubs.org
Purpose To update the recommendations for the use of tumor marker tests in the prevention,
screening, treatment, and surveillance of breast cancer. Methods For the 2007 update, an …

3D microfilter device for viable circulating tumor cell (CTC) enrichment from blood

S Zheng, HK Lin, B Lu, A Williams, R Datar… - Biomedical …, 2011 - Springer
Detection of circulating tumor cells has emerged as a promising minimally invasive
diagnostic and prognostic tool for patients with metastatic cancers. We report a novel three …

Membrane microfilter device for selective capture, electrolysis and genomic analysis of human circulating tumor cells

S Zheng, H Lin, JQ Liu, M Balic, R Datar… - … of chromatography A, 2007 - Elsevier
This paper presents development of a parylene membrane microfilter device for single stage
capture and electrolysis of circulating tumor cells (CTCs) in human blood, and the potential …

Double spiral microchannel for label-free tumor cell separation and enrichment

J Sun, M Li, C Liu, Y Zhang, D Liu, W Liu, G Hu… - Lab on a Chip, 2012 - pubs.rsc.org
This work reports on a passive double spiral microfluidic device allowing rapid and label-
free tumor cell separation and enrichment from diluted peripheral whole blood, by exploiting …

Microfluidic technologies for circulating tumor cell isolation

H Cho, J Kim, H Song, KY Sohn, MH Jeon, KH Han - Analyst, 2018 - pubs.rsc.org
Metastasis is the main cause of tumor-related death, and the dispersal of tumor cells through
the circulatory system is a critical step in the metastatic process. Early detection and analysis …

Recent advances in microfluidic platforms applied in cancer metastasis: Circulating tumor cells'(CTCs) isolation and tumor‐on‐a‐chip

Z Lin, G Luo, W Du, T Kong, C Liu, Z Liu - Small, 2020 - Wiley Online Library
Cancer remains the leading cause of death worldwide despite the enormous efforts that are
made in the development of cancer biology and anticancer therapeutic treatment …

Circulating tumor cells: a multifunctional biomarker

TA Yap, D Lorente, A Omlin, D Olmos… - Clinical Cancer Research, 2014 - AACR
One of the most promising developments in translational cancer medicine has been the
emergence of circulating tumor cells (CTC) as a minimally invasive multifunctional …

Label-free cancer cell separation from human whole blood using inertial microfluidics at low shear stress

MG Lee, JH Shin, CY Bae, S Choi, JK Park - Analytical chemistry, 2013 - ACS Publications
We report a contraction–expansion array (CEA) microchannel device that performs label-
free high-throughput separation of cancer cells from whole blood at low Reynolds number …

Circulating tumor cells in breast cancer: correlation to bone marrow micrometastases, heterogeneous response to systemic therapy and low proliferative activity

V Müller, N Stahmann, S Riethdorf, T Rau… - Clinical Cancer …, 2005 - AACR
Purpose: The incidence and biological characteristics of circulating tumor cells in the blood
of patients with breast cancer were examined and subgroups were evaluated in the context …