Overview of the 2022 WHO classification of pituitary tumors

SL Asa, O Mete, A Perry, RY Osamura - Endocrine pathology, 2022 - Springer
This review summarizes the changes in the 5th Edition of the WHO Classification of
Endocrine and Neuroendocrine Tumors that relate to the pituitary gland. The new …

[HTML][HTML] The complex histopathological and immunohistochemical spectrum of neuroendocrine tumors—an overview of the latest classifications

AA Gheorghișan-Gălățeanu, A Ilieșiu… - International Journal of …, 2023 - mdpi.com
Neuroendocrine neoplasms (NENs) originate from the neuroendocrine cell system, which
may either take the shape of organoid cell aggregations or be composed of dispersed cells …

Preoperatively predicting Ki67 expression in pituitary adenomas using deep segmentation network and radiomics analysis based on multiparameter MRI

H Li, Z Liu, F Li, F Shi, Y Xia, Q Zhou, Q Zeng - Academic Radiology, 2024 - Elsevier
Rationale and Objectives Ki67 proliferation index is associated with more aggressive tumor
behavior and recurrence of pituitary adenomas (PAs). Recently, radiomics and deep …

[HTML][HTML] Relevance of mutations in protein deubiquitinases genes and TP53 in corticotroph pituitary tumors

M Pękul, M Szczepaniak, P Kober… - Frontiers in …, 2024 - frontiersin.org
Introduction Corticotroph pituitary neuroendocrine tumors (PitNETs) develop from ACTH-
producing cells. They commonly cause Cushing's disease (CD), however, some remain …

[HTML][HTML] The expression of glucocorticoid and mineralocorticoid receptors in pituitary tumors causing Cushing's disease and silent corticotroph tumors

P Kober, N Rusetska, BJ Mossakowska… - Frontiers in …, 2023 - frontiersin.org
Objective Pituitary neuroendocrine corticotroph tumors commonly cause Cushing's disease
(CD) that results from increased adrenocorticotropic hormone (ACTH) secretion by the …

[HTML][HTML] Granulation Patterns of Functional Corticotroph Tumors Correlate with Tumor Size, Proliferative Activity, T2 Intensity-to-White Matter Ratio, and Postsurgical …

ET Durmuş, M Kefeli, O Mete, S Çalışkan, K Aslan… - Endocrine …, 2024 - Springer
Unlike somatotroph tumors, the data on correlates of tumor granulation patterns in functional
TPIT lineage pituitary neuroendocrine tumors (corticotroph tumors) have been less uniformly …

E-cadherin expression and gene expression profiles in corticotroph pituitary neuroendocrine tumor subtypes

K Kiseljak-Vassiliades, K Lipe, CG Turin… - … of Neuropathology & …, 2024 - academic.oup.com
Corticotroph adenomas/pituitary neuroendocrine tumors (PitNETs) are associated with
significant morbidity and mortality. Predictors of tumor behavior have not shown high …

[HTML][HTML] Determinants of Clinical Behavior and Prognosis in Cushing's Disease: A Quest for Useful Biomarkers

LC Hernández-Ramírez - Revista de investigación clínica, 2022 - scielo.org.mx
Cushing's disease (CD) is the most common cause of endogenous hypercortisolemia. The
clinical management of this condition is complex and entails multiple therapeutic strategies …

[HTML][HTML] 垂体ACTH 瘤病理评估研究进展

计铭钰, 杨宇宏, 孙敏 - 南京医科大学学报(自然科学版), 2024 - jnmu.njmu.edu.cn
摘要分泌促肾上腺皮质激素(adrenocorticotropic hormone, ACTH) 的垂体腺瘤(垂体ACTH 瘤)
因过度分泌ACTH 刺激双侧肾上腺皮质增生而引起高皮质醇血症, 也称作库欣病(Cushing's …

[HTML][HTML] Sparsely granulated corticotroph pituitary macroadenoma presenting with pituitary apoplexy resulting in remission of hypercortisolism

T Liu, JP Rossiter, RL Houlden, S Awad - AACE Clinical Case Reports, 2022 - Elsevier
Objective Pituitary corticotroph macroadenomas, which account for 7% to 23% of
corticotroph adenomas, rarely present with apoplexy. This report aimed to describe a patient …