Berberine: a review of its pharmacokinetics properties and therapeutic potentials in diverse vascular diseases

X Ai, P Yu, L Peng, L Luo, J Liu, S Li, X Lai… - Frontiers in …, 2021 - frontiersin.org
Traditional Chinese medicine plays a significant role in the treatment of various diseases
and has attracted increasing attention for clinical applications. Vascular diseases affecting …

[HTML][HTML] The mechanism of berberine alleviating metabolic disorder based on gut microbiome

H Wang, H Zhang, Z Gao, Q Zhang… - Frontiers in cellular and …, 2022 - frontiersin.org
With socioeconomic advances and improved living standards, metabolic syndrome has
increasingly come into the attention. In recent years, accumulating evidence has …

Berberine is a suppressor of Hedgehog signaling cascade in colorectal cancer

Q Sun, Q Tao, T Ming, S Tang, H Zhao, M Liu, H Yang… - Phytomedicine, 2023 - Elsevier
Background Colorectal cancer (CRC) is a malignant affliction that burdens people globally.
Overactivated Hedgehog signal is highly implicated in CRC pathogenesis. Phytochemical …

Apoptosis induction, a sharp edge of berberine to exert anti-cancer effects, focus on breast, lung, and liver cancer

Y Zhu, N Xie, Y Chai, Y Nie, K Liu, Y Liu… - Frontiers in …, 2022 - frontiersin.org
Cancer is the leading cause of death and one of the greatest barriers to increased life
expectancy worldwide. Currently, chemotherapy with synthetic drugs remains one of the …

Exogenous melatonin protects preimplantation embryo development from decabromodiphenyl ethane-induced circadian rhythm disorder and endogenous melatonin …

F Shi, J Qiu, S Zhang, X Zhao, D Feng, X Feng - Environmental Pollution, 2022 - Elsevier
Decabromodiphenyl ethane (DBDPE) is a novel flame retardant that is widely used in
plastics, electronic products, building materials and textiles. Our previous studies have …

[HTML][HTML] Melatonin mitigated circadian disruption and cardiovascular toxicity caused by 6-benzylaminopurine exposure in zebrafish

M Yang, J Huang, S Zhang, X Zhao, D Feng… - … and Environmental Safety, 2021 - Elsevier
As a highly effective plant hormone, the overuse of 6-benzylaminopurine (6-BA) may pose
potential threats to organisms and the environment. Melatonin is widely known for its …

CRISPR/Cas9-Induced Inactivation of the Autism-Risk Gene setd5 Leads to Social Impairments in Zebrafish

C Gabellini, C Pucci, C De Cesari, D Martini… - International Journal of …, 2022 - mdpi.com
Haploinsufficiency of the SETD5 gene, encoding a SET domain-containing histone
methyltransferase, has been identified as a cause of intellectual disability and Autism …

Berberine hydrochloride inhibits migration ability via increasing inducible NO synthase and peroxynitrite in HTR-8/SVneo cells

LJ Yang, JB He, Y Jiang, J Li, ZW Zhou, C Zhang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Inadequate trophoblasts migration and invasion is
considered as an initial event resulting in preeclampsia, which is closely related to oxidative …

Robotic cardinal vein microinjection of zebrafish larvae based on 3D positioning

M Sun, L Li, Y Yao, Y Wang, H Gong… - … on Robotics and …, 2021 - ieeexplore.ieee.org
Zebrafish (Danio Rerio) larvae have long been an important model organism for
biomedicine and drug discovery. It is difficult to deliver the external materials into the …

Antioxidant and Cytotoxic Properties of Berberis vulgaris (L.) Stem Bark Dry Extract

IM Ivan, OT Olaru, V Popovici, CL Chițescu… - Molecules, 2024 - mdpi.com
Berberis vulgaris (L.) has remarkable ethnopharmacological properties and is widely used
in traditional medicine. The present study investigated B. vulgaris stem bark (Berberidis …