[HTML][HTML] From synapses to circuits, astrocytes regulate behavior

KA Lyon, NJ Allen - Frontiers in neural circuits, 2022 - frontiersin.org
Astrocytes are non-neuronal cells that regulate synapses, neuronal circuits, and behavior.
Astrocytes ensheath neuronal synapses to form the tripartite synapse where astrocytes …

Chemogenetic modulation of astrocytes and microglia: State‐of‐the‐art and implications in neuroscience

J Bossuyt, Y Van Den Herrewegen, L Nestor, A Buckinx… - Glia, 2023 - Wiley Online Library
Insights into the role astrocytes and microglia play in normal and diseased brain functioning
has expanded drastically over the last decade. Recently, chemogenetic tools have emerged …

Resolving heterogeneity in schizophrenia through a novel systems approach to brain structure: individualized structural covariance network analysis

Z Liu, L Palaniyappan, X Wu, K Zhang, J Du… - Molecular …, 2021 - nature.com
Reliable mapping of system-level individual differences is a critical first step toward
precision medicine for complex disorders such as schizophrenia. Disrupted structural …

Astrocyte activities in the external globus pallidus regulate action-selection strategies in reward-seeking behaviors

S Kang, SI Hong, S Kang, M Song, MA Yang… - Science …, 2023 - science.org
An imbalance in goal-directed and habitual behavioral control is a hallmark of decision-
making–related disorders, including addiction. Although external globus pallidus (GPe) is …

[HTML][HTML] External globus pallidus input to the dorsal striatum regulates habitual seeking behavior in male mice

M Baker, S Kang, SI Hong, M Song, MA Yang… - Nature …, 2023 - nature.com
The external globus pallidus (GPe) coordinates action-selection through GABAergic
projections throughout the basal ganglia. GPe arkypallidal (arky) neurons project exclusively …

[HTML][HTML] Chemogenetic activation of astrocytes in the basolateral amygdala contributes to fear memory formation by modulating the amygdala–prefrontal cortex …

Z Lei, L Xie, CH Li, YY Lam, AS Ramkrishnan… - International Journal of …, 2022 - mdpi.com
The basolateral amygdala (BLA) is one of the key brain areas involved in aversive learning,
especially fear memory formation. Studies of aversive learning in the BLA have largely …

Control of complex behavior by astrocytes and microglia

PI Ortinski, KJ Reissner, J Turner, TL Anderson… - Neuroscience & …, 2022 - Elsevier
Evidence that glial cells influence behavior has been gaining a steady foothold in scientific
literature. Out of the five main subtypes of glial cells in the brain, astrocytes and microglia …

Astrocytes modulate extracellular neurotransmitter levels and excitatory neurotransmission in dorsolateral striatum via dopamine D2 receptor signaling

L Adermark, O Lagström, A Loftén, V Licheri… - …, 2022 - nature.com
Astrocytes provide structural and metabolic support of neuronal tissue, but may also be
involved in shaping synaptic output. To further define the role of striatal astrocytes in …

Astrocytes as Drivers and Disruptors of Behavior: New Advances in Basic Mechanisms and Therapeutic Targeting

D Barnett, K Bohmbach, V Grelot, A Charlet… - Journal of …, 2023 - Soc Neuroscience
Astrocytes are emerging as key regulators of cognitive function and behavior. This review
highlights some of the latest advances in the understanding of astrocyte roles in different …

[HTML][HTML] Alcohol-induced neuroinflammatory response and mitochondrial dysfunction on aging and Alzheimer's disease

BE León, S Kang, G Franca-Solomon… - Frontiers in Behavioral …, 2022 - frontiersin.org
Mitochondria are essential organelles central to various cellular functions such as energy
production, metabolic pathways, signaling transduction, lipid biogenesis, and apoptosis. In …