Astrocytes are emerging as key regulators of cognitive function and behavior. This review
highlights some of the latest advances in the understanding of astrocyte roles in different …

Mutations in the activity-dependent transcription factor MEF2C have been associated with
several neuropsychiatric disorders. Among these, autism spectrum disorder (ASD)-related …

Striatal adenosine A1 receptor (A1R) activation can inhibit dopamine release. A1Rs on other
striatal neurons are activated by an adenosine tone that is limited by equilibrative …

GnRH neurons are the final central neural output regulating fertility. Kisspeptin neurons in
the hypothalamic arcuate nucleus (KNDy neurons) are considered the main regulator of …

Astrocytes are present throughout the brain and intimately interact with neurons and blood
vessels. Three decades of research have shown that astrocytes reciprocally communicate …

In the striatum, two main types of GABAergic medium spiny neurons (MSNs), denoted
striatonigral (or direct-pathway MSNs, dMSNs) and striatopallidal neurons (indirect-pathway …

Opioid abuse and addiction have become a global pandemic, posing tremendous health
and social burdens. The rewarding effects and the occurrence of withdrawal symptoms are …

Astrocytes play a major role in brain function and alterations in astrocyte function that
contribute to the pathogenesis of many brain disorders. The astrocytes are attractive cellular …

Astroglia are key regulators of synaptic function, playing central roles in homeostatic ion
buffering, energy dynamics, transmitter uptake, maintenance of neurotransmitter pools, and …

The initial exploration using pharmacological tools of the role of adenosine receptors in the
brain, concluded that adenosine released as such acted on A 1 R to inhibit excitability and …