[HTML][HTML] Emerging nondopaminergic medications for Parkinson's disease: focusing on A2A receptor antagonists and GLP1 receptor agonists
Parkinson's disease (PD) is a severe neurodegenerative disease characterized by classic
motor features associated with the loss of dopaminergic neurons and appearance of Lewy …
motor features associated with the loss of dopaminergic neurons and appearance of Lewy …
Pan‐striatal reduction in the expression of the astrocytic dopamine transporter precedes the development of dorsolateral striatum dopamine‐dependent incentive …
The emergence of compulsive drug‐seeking habits, a hallmark feature of substance use
disorder, has been shown to be predicated on the engagement of dorsolateral striatal …
disorder, has been shown to be predicated on the engagement of dorsolateral striatal …
A Novel Heuristic Exploration Method Based on Action Effectiveness Constraints to Relieve Loop Enhancement Effect in Reinforcement Learning with Sparse …
Z Ni, Y Jin, P Liu, W Zhao - Cognitive Computation, 2024 - Springer
In realistic sparse reward tasks, existing theoretical methods cannot be effectively applied
due to the low sampling probability ofrewarded episodes. Profound research on methods …
due to the low sampling probability ofrewarded episodes. Profound research on methods …
[HTML][HTML] Astrocytes: Role in pathogenesis and effect of commonly misused drugs in the HIV infected brain
J Pla-Tenorio, AM Roig, PA García-Cesaní… - Current Research in …, 2023 - Elsevier
The roles of astrocytes as reservoirs and producers of a subset of viral proteins in the HIV
infected brain have been studied extensively as a key to understanding HIV-associated …
infected brain have been studied extensively as a key to understanding HIV-associated …
Astrocyte adenosine signaling and neural mechanisms of goal-directed and habitual reward-seeking behaviors
While goal-directed behaviors pursue maximized reward through action–outcome
contingency, repeated behaviors often produce invariances between action and outcome …
contingency, repeated behaviors often produce invariances between action and outcome …
N6-substituated adenosine analog J4 attenuates anxiety-like behaviors in mice
Rationale Withdrawal from chronic alcohol exposure produces various physical and mental
withdrawal symptoms. Activation of adenosine receptors is known to inhibit withdrawal …
withdrawal symptoms. Activation of adenosine receptors is known to inhibit withdrawal …
Astrocytes in neural circuits controlling appetite and food intake
KLJ Ellacott - Current Opinion in Endocrine and Metabolic Research, 2022 - Elsevier
The regulation of feeding behaviour is a complex process controlled by neural circuits in the
brain. In addition to neurons, genetic and pharmacological studies in animal models are …
brain. In addition to neurons, genetic and pharmacological studies in animal models are …
[PDF][PDF] Astrocytes in the external globus pallidus coordinate flexibility of action strategy
The external globus pallidus (GPe) is an integrative hub and gateway for behavioral exibility
in rewardrelated behaviors. However, it remains unknown whether enriched astrocytes in …
in rewardrelated behaviors. However, it remains unknown whether enriched astrocytes in …
Dual role of striatal astrocytes in behavioral flexibility and metabolism in the context of obesity
E Montalban, DHM Chao, A Ansoult, C Pham, A Contini… - bioRxiv, 2023 - biorxiv.org
Brain circuits involved in metabolic control and reward-associated behaviors are potent
drivers of feeding behavior and are both dramatically altered in obesity, a multifactorial …
drivers of feeding behavior and are both dramatically altered in obesity, a multifactorial …
Astrocytic Bestrophin1 in the Anterior Cingulate Cortex Modulates the Formation and Persistence of Morphine Addiction Memory
L Sun, Z Liu, Y Li, X Lin, Y Huo, S Guo, X Fan, X Ye… - 2024 - researchsquare.com
Emerging evidence indicates that astrocytes play a vital role in both the establishment and
preservation of memories. However, their specific contribution to addiction-related memory …
preservation of memories. However, their specific contribution to addiction-related memory …