[HTML][HTML] Tumor-associated neutrophils in colorectal cancer development, progression and immunotherapy

W Zheng, J Wu, Y Peng, J Sun, P Cheng, Q Huang - Cancers, 2022 - mdpi.com
Simple Summary Tumor-associated neutrophils (TANs) may differentiate into different
patterns under the stimulation of different factors, and they play a dual role in the occurrence …

Drug-induced liver injury and anti-hepatotoxic effect of herbal compounds: a metabolic mechanism perspective

J Rani, SB Dhull, PK Rose, MK Kidwai - Phytomedicine, 2024 - Elsevier
Background Drug-induced liver injury (DILI) is the most challenging and thought-provoking
liver problem for hepatologists owing to unregulated medication usage in medical practices …

[HTML][HTML] Screening for susceptibility-related biomarkers of diclofenac-induced liver injury in rats using metabolomics

C Tu, Y Gao, D Song, M Niu, R Ma, M Zhou… - Frontiers in …, 2021 - frontiersin.org
Early identification of individuals susceptible to idiosyncratic drug-induced liver injury (IDILI)
is a challenging unmet demand. Diclofenac, one of the most widely available over-the …

Evaluating the protective effect of metformin against diclofenac-induced oxidative stress and hepatic damage: In vitro and in vivo studies

MH Darijani, A Aminzadeh, HR Rahimi… - Biochemical and …, 2023 - Elsevier
Diclofenac (DIC) is one of the most commonly prescribed non-steroidal anti-inflammatory
drugs and has been shown to cause oxidative stress and liver injury. The current study …

Targeting inhibition of CCR5 on improving obesity-associated insulin resistance and impairment of pancreatic insulin secretion in high fat-fed rodent models

PC Chan, MT Liao, CH Lu, YF Tian, PS Hsieh - European Journal of …, 2021 - Elsevier
Obesity is closely linked with type 2 diabetes and the effective therapies on obesity-
associated diabetes are under development. The aim of this study was undertaken to …

Preparation, Characterization, and Properties of Inclusion Complexes of Balofloxacin with Cyclodextrins

X Ren, H Qian, P Tang, Y Tang, Y Liu, H Pu… - AAPS …, 2019 - Springer
The study mainly aimed to improve the aqueous solubility of Balofloxacin (BLFX) by
preparing the inclusion complexes (ICs) of BLFX with cyclodextrins (CDs). In this study, ICs …

[HTML][HTML] CCR5 拮抗剂新药理作用及机制研究进展

郑玉贵, 陈欢, 罗荣华, 郑昌博 - 2020 - html.rhhz.net
CC 趋化因子受体5 (CC chemokine receptor 5, CCR5) 是G 蛋白偶联受体家族成员,
在多种细胞表面表达, CCR5 与其特异性配体结合而发挥生物学作用. 随着对CCR5 …

Unveiling the Hub Genes Associated with Manganese-Induced Hepatotoxicity

B Yang, Z Hu, S Wang, X Shi, X Li - 2023 - researchsquare.com
Excessive exposure to manganese (Mn) can cause severe toxicity in human and animal
organs, particularly the liver. However, the specific mechanisms of Mn-induced …

[PDF][PDF] Anatomical and Histological Effects of Nonsteroidal Anti-inflammatory Drugs Injection on Sciatic Nerve of Rats

MMH Taha, AHQ Sulaiman - researchgate.net
Injury to peripheral nerves is a clinical complication after intramuscular injections, where
sciatic nerve is considered to be the most frequent nerve involved following intramuscular …