Dietary polyphenols and their role in oxidative stress-induced human diseases: Insights into protective effects, antioxidant potentials and mechanism (s) of action

M Rudrapal, SJ Khairnar, J Khan, AB Dukhyil… - Frontiers in …, 2022 - frontiersin.org
Dietary polyphenols including phenolic acids, flavonoids, catechins, tannins, lignans,
stilbenes, and anthocyanidins are widely found in grains, cereals, pulses, vegetables …

Metabolic syndrome and cardiovascular diseases: Going beyond traditional risk factors

JL Silveira Rossi, SM Barbalho… - Diabetes/metabolism …, 2022 - Wiley Online Library
Metabolic syndrome (MS) is a chronic non‐infective syndrome characterised clinically by a
set of vascular risk factors that include insulin resistance, hypertension, abdominal obesity …

[PDF][PDF] Extracellular vesicle-based interorgan transport of mitochondria from energetically stressed adipocytes

C Crewe, JB Funcke, S Li, N Joffin, CM Gliniak… - Cell metabolism, 2021 - cell.com
Adipocytes undergo intense energetic stress in obesity resulting in loss of mitochondrial
mass and function. We have found that adipocytes respond to mitochondrial stress by …

[HTML][HTML] Reactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries

T Zhao, W Wu, L Sui, Q Huang, Y Nan, J Liu, K Ai - Bioactive Materials, 2022 - Elsevier
Interventional coronary reperfusion strategies are widely adopted to treat acute myocardial
infarction, but morbidity and mortality of acute myocardial infarction are still high …

Oxidative stress in cardiovascular diseases

E Dubois-Deruy, V Peugnet, A Turkieh, F Pinet - Antioxidants, 2020 - mdpi.com
Reactive oxygen species (ROS) are subcellular messengers in signal transductions
pathways with both beneficial and deleterious roles. ROS are generated as a by-product of …

[HTML][HTML] Oxidative stress–Complex pathological issues concerning the hallmark of cardiovascular and metabolic disorders

D Rotariu, EE Babes, DM Tit, M Moisi, C Bustea… - Biomedicine & …, 2022 - Elsevier
Oxidative stress is a complex biological process characterized by the excessive production
of reactive oxygen species (ROS) that act as destroyers of the REDOX balance in the body …

The role of glutathione peroxidase-1 in health and disease

DE Handy, J Loscalzo - Free Radical Biology and Medicine, 2022 - Elsevier
Abstract Glutathione peroxidase 1 (GPx1) is an important cellular antioxidant enzyme that is
found in the cytoplasm and mitochondria of mammalian cells. Like most selenoenzymes, it …

Lycopene in the prevention of cardiovascular diseases

S Przybylska, G Tokarczyk - International Journal of Molecular Sciences, 2022 - mdpi.com
Cardiovascular diseases (CVDs) are the leading cause of human mortality worldwide.
Oxidative stress and inflammation are pathophysiological processes involved in the …

[HTML][HTML] ROS systems are a new integrated network for sensing homeostasis and alarming stresses in organelle metabolic processes

Y Sun, Y Lu, J Saredy, X Wang, C Drummer IV, Y Shao… - Redox biology, 2020 - Elsevier
Reactive oxygen species (ROS) are critical for the progression of cardiovascular diseases,
inflammations and tumors. However, the mechanisms of how ROS sense metabolic stress …

Oxidative stress-induced endothelial dysfunction in cardiovascular diseases

A Shaito, K Aramouni, R Assaf, A Parenti, A Orekhov… - 2022 - qspace.qu.edu.qa
Cardiovascular disease (CVD) is a major cause of mortality worldwide. A better
understanding of the mechanisms underlying CVD is key for better management or …