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Activation of the classical pathway of the complement system is initiated by the binding of
C1q to antibody complexes. Here we evaluated the C1q binding capacity of series of …

The Antibodies presents models, theories, and techniques of molecular biology for
understanding the mechanisms of antibody action, including the genetics, and receptor and …

To overcome the disadvantages of bi-specific antibody methodologies in vivo, a novel
antibody approach has been designed to improve tumour targeting and effector to target …

Bifunctional antibodies are monovalent, bispecific, antibody-derived molecules. They have
been produced by both chemical and biological means. They are thought to have several …

Two lines of mouse-human hybridomas were fused to produce human bifunctional
antibodies. A hybridoma that secretes human IgM (κ) class antiricin monoclonal antibody …

Bacterial encoded superantigens (SA) are capable of activating and targeting cytolytic
human and mouse T lymphocytes (CTL) to lyse major histocompatibility complex class II …

Techniques of genetic engineering, homologous recombination, and gene transfection
make it feasible to produce antigen-binding molecules with widely varying structures. Novel …

Two cell lines of human hybridomas were fused to generate hybrid antibodies. One human
hybridoma cell line was HT2 producing IgM monoclonal antibody (MAb) reactive to carboxy …