[HTML][HTML] Bioactivity, Molecular Mechanism, and Targeted Delivery of Flavonoids for Bone Loss

AR Sharma, YH Lee, A Bat-Ulzii, S Chatterjee… - Nutrients, 2023 - mdpi.com
Skeletal disabilities are a prominent burden on the present population with an increasing life
span. Advances in osteopathy have provided various medical support for bone-related …

[HTML][HTML] Pharmacological and mechanistic aspects of quercetin in osteoporosis

TT Deng, WY Ding, XX Lu, QH Zhang, JX Du… - Frontiers in …, 2024 - frontiersin.org
Osteoporosis (OP) is a bone disease associated with increasing age. Currently, the most
common medications used to treat OP are anabolic agents, anti-resorptive agents, and …

[HTML][HTML] Gut metabolite urolithin A inhibits osteoclastogenesis and senile osteoporosis by enhancing the autophagy capacity of bone marrow macrophages

H Tao, Y Tao, C Yang, W Li, W Zhang, X Li… - Frontiers in …, 2022 - frontiersin.org
Senile osteoporosis (SOP) is a systemic bone disease that is significantly associated with
age and eventually leads to deteriorated bone strength and increased fracture risk. Urolithin …

[HTML][HTML] Discovery of genistein derivatives as potential SARS-CoV-2 main protease inhibitors by virtual screening, molecular dynamics simulations and ADMET …

J Liu, L Zhang, J Gao, B Zhang, X Liu, N Yang… - Frontiers in …, 2022 - frontiersin.org
Background: Due to the constant mutation of virus and the lack of specific therapeutic drugs,
the coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory …

[HTML][HTML] Corylifol A suppresses osteoclastogenesis and alleviates ovariectomy-induced bone loss via attenuating ROS production and impairing mitochondrial …

HS Li, W Deng, JM Yang, YW Lin, SY Zhang… - Biomedicine & …, 2024 - Elsevier
Osteoporosis is a systemic disease characterized by an imbalance in bone homeostasis,
where osteoblasts fail to fully compensate for the bone resorption induced by osteoclasts …

2, 4′-Dihydroxybenzophenone Exerts Bone Formation and Antiosteoporotic Activity by Stimulating the β-Catenin Signaling Pathway

MHD Kavinda, MH Lee, CH Kang… - ACS Pharmacology & …, 2024 - ACS Publications
2, 4′-Dihydroxybenzophenone (DHP) is an organic compound derived from Garcinia
xanthochymus, but there have been no reports on its biochemical functions and …

[HTML][HTML] Flavonoids from Dalbergia cochinchinensis: Impact on osteoclastogenesis

F Shao, L Panahipour, R Gruber - Journal of dental sciences, 2023 - Elsevier
Background/purpose Dalbergia cochinchinensi has been widely used in traditional
medicine because of its flavonoids. This study examined which components in D …

[PDF][PDF] Bioactivity, Molecular Mechanism, and Targeted Deliv-ery of Flavonoids for Bone Loss. Nutrients 2023, 15, 919

AR Sharma, YH Lee, A Bat-Ulzii, S Chatterjee… - 2023 - researchgate.net
Skeletal disabilities are a prominent burden on the present population with an increasing life
span. Advances in osteopathy have provided various medical support for bone-related …

Anti-inflammatory and anti-osteoporotic effects of 2, 4'-dihydroxybenzophenone

MHD Kavinda - 2023 - oldlib.jejunu.ac.kr
2, 4′-Dihydroxybenzophenone (DHP) is derived from the herbs of Garcinia xanthochymus;
no biochemical properties have been elucidated. In this study, we investigated whether DHP …

Carnosic acid inhibits osteoclast differentiation by inhibiting mitochondrial activity

H Li, Y Wu, Z Liang, S Zhang, Z Zhang, B Mai… - Chinese Journal of …, 2025 - cjter.com
BACKGROUND: Carnosic acid, a bioactive compound found in rosemary, has been shown
to reduce inflammation and reactive oxygen species (ROS). However, its mechanism of …