In recent decades, cancer research has expanded exponentially beyond the study of
abnormally dividing cells to include complex and extensive heterotypic interactions between …

Perineural invasion (PNI) is the process of neoplastic invasion of peripheral nerves and is
considered to be the fifth mode of cancer metastasis. PNI has been detected in head and …

Intercellular communication plays an important role in cancer initiation and progression
through direct contact and indirect interactions, such as via secretory molecules. Cancer …

Communication networks in the tumor microenvironment (TME) play a crucial role in tumor
progression. Cancer-associated fibroblasts (CAFs) are among the most abundant stromal …

The runt-related transcription factor-1 (RUNX1) gene with its lncRNA RUNXOR are recently
becoming a research focus in various diseases, specifically immune-related diseases as …

Salivary adenoid cystic carcinoma (SACC) is one of the most common salivary gland
malignancies. Current clinical therapies have limitations and cannot efficiently prevent the …

Extracellular vesicles (EVs) are a class of nanoparticles that are derived from almost any
type of cell in the organism tested thus far and are present in all body fluids. With the …

Simple Summary Pancreatic cancer is a highly lethal malignant disease with a dense
stroma, called the tumor microenvironment. Accumulating evidence indicates the important …

Head and neck cancer (HNC) is a fatal and debilitating disease that is characterized by
steady, poor survival rates despite advances in treatment. There is an urgent and unmet …

Background Neurotrophic tropomyosin receptor kinases (NTRKs) are a gene family function
as oncogene or tumor suppressor gene in distinct cancers. We aimed to investigate the …