Vascularized organ bioprinting: From strategy to paradigm
Over the past two decades, 3D bioprinting has become a popular research topic worldwide,
as it is the most promising approach for manufacturing vascularized organs in vitro …
as it is the most promising approach for manufacturing vascularized organs in vitro …
Beyond the Final Heartbeat: Neurological Perspectives on Normothermic Regional Perfusion for Organ Donation after Circulatory Death
MP Kirschen, A Lewis, MA Rubin… - Annals of …, 2024 - Wiley Online Library
Normothermic regional perfusion (NRP) has recently been used to augment organ donation
after circulatory death (DCD) to improve the quantity and quality of transplantable organs. In …
after circulatory death (DCD) to improve the quantity and quality of transplantable organs. In …
[HTML][HTML] Development of a Novel Perfusable Solution for ex vivo Preservation: Towards Photosynthetic Oxygenation for Organ Transplantation
V Veloso-Giménez, R Escamilla, D Necuñir… - … in Bioengineering and …, 2021 - frontiersin.org
Oxygen is the key molecule for aerobic metabolism, but no animal cells can produce it,
creating an extreme dependency on external supply. In contrast, microalgae are …
creating an extreme dependency on external supply. In contrast, microalgae are …
Normothermic Ex Vivo Heart Perfusion with Mesenchymal Stem Cell‐Derived Conditioned Medium Improves Myocardial Tissue Protection in Rat Donation after …
Z Zeng, L Xu, Y Xu, Y Ruan, D Liu, J Li… - Stem Cells …, 2022 - Wiley Online Library
Objective. Adopting hearts from donation after circulatory death (DCD) is a promising
approach to enlarge the donor pool. Nevertheless, DCD hearts experience severe warm …
approach to enlarge the donor pool. Nevertheless, DCD hearts experience severe warm …
Emerging talents in alloimmunity and transplantation: 2022
G Moll, WH Lim, O Penack - Frontiers in Immunology, 2024 - frontiersin.org
In modern transplant and biomedicine, a proper understanding of both allo-and autoimmune
processes is of key importance to minimize acute and chronic graft failure and consecutive …
processes is of key importance to minimize acute and chronic graft failure and consecutive …
[HTML][HTML] Donor heart ischemic time can be extended beyond 9 hours using hypothermic machine perfusion in sheep
Background The global shortage of donor hearts available for transplantation is a major
problem for the treatment of end-stage heart failure. The ischemic time for donor hearts …
problem for the treatment of end-stage heart failure. The ischemic time for donor hearts …
Inflation using hydrogen improves donor lung quality by regulating mitochondrial function during cold ischemia phase
L Duan, L Quan, B Zheng, Z Li, G Zhang… - BMC Pulmonary …, 2023 - Springer
Background Mitochondrial dysfunction results in poor organ quality, negatively affecting the
outcomes of lung transplantation. Whether hydrogen benefits mitochondrial function in cold …
outcomes of lung transplantation. Whether hydrogen benefits mitochondrial function in cold …
Adipose-derived stem/stromal cells in kidney transplantation: status quo and future perspectives
G Storti, E Favi, F Albanesi, BS Kim… - International Journal of …, 2021 - mdpi.com
Kidney transplantation (KT) is the gold standard treatment of end-stage renal disease.
Despite progressive advances in organ preservation, surgical technique, intensive care, and …
Despite progressive advances in organ preservation, surgical technique, intensive care, and …
Enzymatic blood group conversion of human kidneys during ex vivo normothermic machine perfusion
S MacMillan, SA Hosgood… - British Journal of …, 2023 - academic.oup.com
A major restriction to transplantation is the requirement for ABO blood group compatibility
between donor and recipient. In this study, an α-galactosidase enzyme from Bacteroides …
between donor and recipient. In this study, an α-galactosidase enzyme from Bacteroides …
Quality of life metrics in LVAD patients after hemocompatibility‐related adverse events
MP Weber, J Stulak, S Maltais, FD Pagani… - Artificial …, 2022 - Wiley Online Library
Background Hemocompatibility‐related adverse events (HRAE) negatively influence
survival. However, no study has examined the impact of these events on health‐related …
survival. However, no study has examined the impact of these events on health‐related …