TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling

A Ciesielska, M Matyjek, K Kwiatkowska - Cellular and molecular life …, 2021 - Springer
Abstract Toll-like receptor (TLR) 4 belongs to the TLR family of receptors inducing pro-
inflammatory responses to invading pathogens. TLR4 is activated by lipopolysaccharide …

Long‐COVID syndrome‐associated brain fog and chemofog: Luteolin to the rescue

TC Theoharides, C Cholevas, K Polyzoidis… - Biofactors, 2021 - Wiley Online Library
COVID‐19 leads to severe respiratory problems, but also to long‐COVID syndrome
associated primarily with cognitive dysfunction and fatigue. Long‐COVID syndrome …

Toll-like receptors in immunity and inflammatory diseases: Past, present, and future

K Vijay - International immunopharmacology, 2018 - Elsevier
The immune system is a very diverse system of the host that evolved during evolution to
cope with various pathogens present in the vicinity of environmental surroundings inhabited …

Mast cell function: a new vision of an old cell

EZM da Silva, MC Jamur… - Journal of Histochemistry …, 2014 - journals.sagepub.com
Since first described by Paul Ehrlich in 1878, mast cells have been mostly viewed as
effectors of allergy. It has been only in the past two decades that mast cells have gained …

Role of reactive oxygen and nitrogen species in the vascular responses to inflammation

PR Kvietys, DN Granger - Free Radical Biology and Medicine, 2012 - Elsevier
Inflammation is a complex and potentially life-threatening condition that involves the
participation of a variety of chemical mediators, signaling pathways, and cell types. The …

[HTML][HTML] Cre-mediated cell ablation contests mast cell contribution in models of antibody-and T cell-mediated autoimmunity

TB Feyerabend, A Weiser, A Tietz, M Stassen, N Harris… - Immunity, 2011 - cell.com
Immunological functions of mast cells remain poorly understood. Studies in Kit mutant mice
suggest key roles for mast cells in certain antibody-and T cell-mediated autoimmune …

TLR signaling in mast cells: common and unique features

H Sandig, S Bulfone-Paus - Frontiers in immunology, 2012 - frontiersin.org
In addition to the well known role of mast cells in immunity to multi-cellular parasites and in
the pathogenesis of allergy and asthma, the importance of mast cells in the immune defense …

Innate immunity and its regulation by mast cells

AL St John, SN Abraham - The Journal of Immunology, 2013 - journals.aai.org
Mast cells (MCs), which are granulated tissue-resident cells of hematopoietic lineage,
constitute a major sensory arm of the innate immune system. In this review we discuss the …

Application of transcriptome analysis: Oxidative stress, inflammation and microtubule activity disorder caused by ammonia exposure may be the primary factors of …

S Wang, X Li, W Wang, H Zhang, S Xu - Science of the Total Environment, 2019 - Elsevier
Abstract Ammonia (NH 3), an inhaled harmful gas, is not only an important volatile in
fertilizer production and ranching, but also the main basic component of haze. However, the …

Responses of mast cells to pathogens: Beneficial and detrimental roles

M Jiménez, D Cervantes-García… - Frontiers in …, 2021 - frontiersin.org
Mast cells (MCs) are strategically located in tissues close to the external environment, being
one of the first immune cells to interact with invading pathogens. They are long living effector …