Antibiotic resistance is a major global health challenge and, worryingly, several key Gram
negative pathogens can become resistant to most currently available antibiotics. Polymyxins …

Antibiotic heteroresistance is a phenotype in which a bacterial isolate contains
subpopulations of cells that show a substantial reduction in antibiotic susceptibility …

Managing Acinetobacter baumannii infections : Current Opinion in Infectious Diseases
Managing Acinetobacter baumannii infections : Current Opinion in Infectious Diseases Log in or …

These updated guidelines from the Infectious Diseases Community of Practice of the
American Society of Transplantation review the diagnosis, prevention, and management of …

Background: Colistin is one of the few remaining options for carbapenem-resistant
Acinetobacter baumannii (A. baumannii); however, emergence of resistance from …

Highlights•Drug combinations improve efficacy and permit dose reductions of each
drug.•Lowering the dose of combined drugs prevents concentration-associated …

Colistin heteroresistance (HR) refers to a bacterial population comprised of several
subpopulations with different levels of resistance to colistin. In this study, we discuss the …

Antimicrobial resistance is a major global health challenge. As few new efficacious
antibiotics will become available in the near future, peptide antibiotics continue to be major …

This study aimed to determine the proportion of heteroresistance in carbapenem-resistant
Acinetobacter calcoaceticus-baumannii complex (CRAB) isolates in the cefiderocol arm of …

Antimicrobial therapy is facing a worrisome and underappreciated challenge, the
phenomenon of heteroresistance (HR). HR has been gradually documented in clinically …