Reactive oxygen species, toxicity, oxidative stress, and antioxidants: Chronic diseases and aging

K Jomova, R Raptova, SY Alomar, SH Alwasel… - Archives of …, 2023 - Springer
A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

Risk factors for severe and critically ill COVID‐19 patients: a review

Y Gao, M Ding, X Dong, J Zhang, A Kursat Azkur… - Allergy, 2021 - Wiley Online Library
The pandemic of coronavirus disease 2019 (COVID‐19), caused by the severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has caused an unprecedented global …

NF‐κB signaling in inflammation and cancer

T Zhang, C Ma, Z Zhang, H Zhang, H Hu - MedComm, 2021 - Wiley Online Library
Since nuclear factor of κ‐light chain of enhancer‐activated B cells (NF‐κB) was discovered
in 1986, extraordinary efforts have been made to understand the function and regulating …

Anti-inflammatory action and mechanisms of resveratrol

T Meng, D Xiao, A Muhammed, J Deng, L Chen, J He - Molecules, 2021 - mdpi.com
Resveratrol (3, 4′, 5-trihy-droxystilbene), a natural phytoalexin polyphenol, exhibits anti-
oxidant, anti-inflammatory, and anti-carcinogenic properties. This phytoalexin is well …

Molecular Landscape of LncRNAs in Prostate Cancer: A focus on pathways and therapeutic targets for intervention

S Mirzaei, MDA Paskeh, E Okina, MH Gholami… - Journal of Experimental …, 2022 - Springer
Background One of the most malignant tumors in men is prostate cancer that is still incurable
due to its heterogenous and progressive natures. Genetic and epigenetic changes play …

Regulation of TNF-induced osteoclast differentiation

Z Yao, SJ Getting, IC Locke - Cells, 2021 - mdpi.com
Increased osteoclast (OC) differentiation and activity is the critical event that results in bone
loss and joint destruction in common pathological bone conditions, such as osteoporosis …

M2b macrophage polarization and its roles in diseases

L Wang, S Zhang, H Wu, X Rong… - Journal of leukocyte …, 2019 - academic.oup.com
Macrophages play an important role in a wide variety of physiologic and pathologic
processes. Plasticity and functional polarization are hallmarks of macrophages …

NF-κB, inflammation, immunity and cancer: coming of age

K Taniguchi, M Karin - Nature Reviews Immunology, 2018 - nature.com
Fourteen years have passed since nuclear factor-κB (NF-κB) was first shown to serve as a
molecular lynchpin that links persistent infections and chronic inflammation to increased …

ROS-scavenging therapeutic hydrogels for modulation of the inflammatory response

YE Kim, J Kim - ACS Applied Materials & Interfaces, 2021 - ACS Publications
Although reactive oxygen species (ROS) are essential for cellular processes, excessive
ROS could be a major cause of various inflammatory diseases because of the oxidation of …

Influence of resveratrol on the immune response

L Malaguarnera - Nutrients, 2019 - mdpi.com
Resveratrol is the most well-known polyphenolic stilbenoid, present in grapes, mulberries,
peanuts, rhubarb, and in several other plants. Resveratrol can play a beneficial role in the …