The interaction between obesity and bone metabolism is complex. The effects of fat on the
skeleton are mediated by both mechanical and biochemical factors. Though obesity is …

Bone homeostasis displays a circadian rhythm with increased resorption during the night
time as compared to day time, a difference that seems—at least partly—to be caused by food …

Some anti-diabetic therapies can have adverse effects on bone health and increase fracture
risk. In this study, we tested the skeletal effects of chronic administration of two Glucagon-like …

Diabetes mellitus is associated with abnormal bone health and an increased risk of fracture
even though patients have normal or higher BMD. The mechanisms behind diabetes …

Gut hormones secreted from enteroendocrine cells following nutrient ingestion modulate
metabolic processes including glucose homeostasis and food intake, and several of these …

The impact of antidiabetic drugs on bone metabolism is drawing increasing attention due to
the discovery of a correlation between type 2 diabetes mellitus (T2DM) and osteoporosis …

Previous studies have proven that glucagon-like peptide-1 (GLP-1) and its receptor agonist
exert favorable anabolic effects on skeletal metabolism. However, whether GLP-1 could …

Background Liraglutide, a glucagon-like peptide-1 receptor agonist, has well known
beneficial effects on glucose metabolism, and animal studies indicate that liraglutide also …

Adiponectin, the most prevalent adipo-cytokine in plasma plays critical metabolic and anti-
inflammatory roles is fast emerging as an important molecular target for the treatment of …

Liraglutide, a glucagon‑like peptide‑1 receptor agonist, is an anti‑diabetic medicine
associated with a reduced risk of fracture in diabetic patients. In the present study, rats with …