Fentanyl is a powerful opioid anesthetic and analgesic, the use of which has caused an
increasing public health threat in the United States and elsewhere. Fentanyl was initially …

Opioid use disorder is classified as a chronic recurrent disease of the central nervous
system (CNS) which leads to personality disorders, co-morbidities and premature death. It …

Opioids are mu receptor agonists and have been an important part of pain treatment for
thousands of years. In order to use these drugs appropriately and successfully in patients …

With a focus on practical acute pain management in adults in the hospital setting, this book
provides health professionals with simple and practical information to help them manage …

Seizures of synthetic opioids have increased since 2012, with a 45% increase in synthetic
opioid related deaths between 2016 and 2017 in US. Recently, concerns have arisen …

Background: New Psychoactive Substances (NPS) constitute a broad range of hundreds of
natural and synthetic drugs, including synthetic opioids, synthetic cannabinoids, synthetic …

Electron Impact Gas Chromatography-Mass Spectrometry (EI-GC-MS) and High Resolution
Liquid Chromatography-Mass Spectrometry (HR-LC-MS) have been used in the analysis of …

Background The comparative efficacy of ancillary drugs on sevoflurane related emergence
agitation (EA) in children undergoing ophthalmic surgery remains controversial. Methods …

Background and Objectives Highly potent synthetic opioids (HPSO) are increasingly
responsible for opioid overdose deaths in the United States. Methods In an open‐label …

Prescription opioid misuse is an ongoing and escalating epidemic. Although these
pharmacological agents are highly effective analgesics prescribed for different types of pain …