Abstract Introduction and Aims There is a current epidemic of pharmaceutical opioid (PO)
misuse, particularly fentanyl and fentanyl analogues, globally. Fentanyl is a highly potent …

Despite advances in medical and interventional management of acute myocardial infarction,
treatment of the associated chest pain has remained relatively unchanged since opioids …

Head and neck cancers (HNC) represent 5% of all malignancies worldwide with about
180,000 cancer deaths per year. Patients with HNC are characterized by a systemic …

Background: Morphine reduces absorption and delays action onset of potent oral P2Y 12
receptor inhibitors in patients with ST-segment elevation myocardial infarction (STEMI). We …

Abstract Background and Objectives Fentanyl and other highly potent synthetic opioids are
the leading cause of opioid overdose deaths in the United States. Methods This study was …

Underlying cancer pain has heterogenous aetiologies and mechanisms. It requires detailed
and comprehensive pain assessment, combined with personalized treatment. A …

Introduction A previous Delphi survey from the Rational Use of Analgesics (RUA) project
involving Italian palliative care specialists revealed some discrepancies between current …

What is known and objective The comparative efficacy of ancillary drugs on sevoflurane‐
related emergence agitation (EA) in paediatric anaesthesia for adenotonsillectomy remains …

Transdermal drug delivery systems (TDDS) are designed to deliver drugs through the skin
and into the systemic circulation. They offer several advantages over traditional oral or …

Pain remains a global health challenge affecting approximately 1.5 billion people
worldwide. Pain has been an implicit variable in the equation of human life for many …