Proteins are nature's primary building blocks for the construction of sophisticated molecular
machines and dynamic materials, ranging from protein complexes such as photosystem II …

Skeletal muscle is one of the most dynamic and plastic tissues of the human body. In
humans, skeletal muscle comprises approximately 40% of total body weight and contains 50 …

Guanine-rich nucleic acid sequences challenge the replication, transcription, and translation
machinery by spontaneously folding into G-quadruplexes, the unfolding of which requires …

Cardiac and skeletal striated muscles are intricately designed machines responsible for
muscle contraction. Coordination of the basic contractile unit, the sarcomere, and the …

Proteins, the most important functional components in muscle, confer many of the desirable
physicochemical and sensory attributes of muscle foods. Muscle proteins comprise 15-22 …

Vigorous transport of cytoplasmic components along axons over substantial distances is
crucial for the maintenance of neuron structure and function. The transport of mitochondria …

Myosin motors power movements on actin filaments, whereas dynein and kinesin motors
power movements on microtubules. The mechanisms of these motor proteins differ, but, in …

Decreased cardiac contractility is a central feature of systolic heart failure. Existing drugs
increase cardiac contractility indirectly through signaling cascades but are limited by their …

Intrinsic disorder refers to segments or to whole proteins that fail to self‐fold into fixed 3D
structure, with such disorder sometimes existing in the native state. Here we report data on …

A new in vitro assay using a feedback enhanced laser trap system allows direct
measurement of force and displacement that results from the interaction of a single myosin …