Genome-wide association studies (GWAS) involve testing genetic variants across the
genomes of many individuals to identify genotype–phenotype associations. GWAS have …

Complex interaction between genetics, epigenetics, environment, and nutrition affect the
physiological activities of adipose tissues and their dysfunctions, which lead to several …

Several animals have been in the limelight of basic research associated with metabolic
diseases like obesity. Obesity can be considered as a significant public health concern in …

Obesity is a worldwide epidemic and contributes to global morbidity and mortality mediated
via the development of nonalcoholic fatty liver disease (NAFLD), type 2 diabetes (T2D) …

Background As obesity is becoming pandemic, morbid obesity (MO), an extreme type of
obesity, is an emerging issue worldwide. It is imperative to understand the factors …

Obesity is a major health condition that affects millions worldwide. There is an increased
interest in understanding the adverse outcomes associated with obesogenic diets. A …

The recent development of next‐generation sequencing (NGS) technologies has led to an
increase of mutation screening reports of monogenic obesity genes in diverse experimental …

Abstract Metabolic Syndrome (MetS) is a highly heritable disease and a major public health
burden worldwide. MetS diagnosis criteria is met by the simultaneous presence of any three …

Patients with monogenic obesity display numerous medical features on top of hyperphagic
obesity, but no study to date has provided an exhaustive description of their semiology. Two …

Most known types of nonsyndromic monogenic obesity are caused by rare mutations in
genes of the leptin‐melanocortin pathway controlling appetite and adiposity. In contrast …