Lupus nephritis (LN) is a major cause of morbidity and mortality among patients with
systemic lupus erythematosus (SLE). However, promising emerging biomarkers pave the …

Autoimmune rheumatic diseases (AIRDs) constitute a set of connective tissue disorders and
dysfunctions with akin clinical manifestations and autoantibody responses. AIRD treatment …

Eosinophilic granulomatosis with polyangiitis (EGPA) causes necrotizing vasculitis and
eosinophil-rich granulomatous inflammation in small-to medium-sized vessels, resulting in …

Anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis is a destructive small
vessel vasculitis affecting multiple organs. Renal involvement often leads to end-stage renal …

Taking into account the suboptimal medium-long term safety profile of conventional EGPA
treatments, the opportunity of selectively targeting eosinophilic inflammation certainly …

Objective Salivary gland involvement in anti-neutrophil cytoplasmic autoantibody (ANCA)-
associated vasculitis is rare, but can lead to the misdiagnosis of other diseases. The …

Recent years have brought progress in understanding the role of the neutrophil, dispelling
the dogma of homogeneous cells mainly involved in the prime defence against pathogens …

Background Ocular manifestations of granulomatosis with polyangiitis (GPA) have been
reported in a limited number of studies and with largely variable frequency. Here we report …

Traumatic brain injury (TBI), characterized by acute neurological impairment, is associated
with a higher incidence of neurodegenerative diseases, particularly chronic traumatic …

In recent years, clinical research has increased significantly and therapies for antineutrophil
cytoplasmic antibody (ANCA)-associated vasculitis have improved. However, there are still …