Facts and recommendations about total homocysteine determinations: an expert opinion

H Refsum, AD Smith, PM Ueland, E Nexo… - Clinical …, 2004 - academic.oup.com
Background: Measurement of plasma total homocysteine has become common as new
methods have been introduced. A wide range of disorders are associated with increased …

Cystathionine β‐Synthase in Physiology and Cancer

H Zhu, S Blake, KT Chan, RB Pearson… - BioMed research …, 2018 - Wiley Online Library
Cystathionine β‐synthase (CBS) regulates homocysteine metabolism and contributes to
hydrogen sulfide (H2S) biosynthesis through which it plays multifunctional roles in the …

Folic acid improves endothelial function in coronary artery disease via mechanisms largely independent of homocysteine lowering

SN Doshi, IFW McDowell, SJ Moat, N Payne… - Circulation, 2002 - Am Heart Assoc
Background—Homocysteine is a risk factor for coronary artery disease (CAD), although a
causal relation remains to be proven. The importance of determining direct causality rests in …

Highly scalable design of 3D copper-doped graphene printed microfluidic chip for the electrochemical quantification of plasma homocysteine

N Karikalan, A Yamuna, TY Lee - Chemical Engineering Journal, 2023 - Elsevier
Elevated levels of plasma homocysteine (Hcy) increase the risk of various diseases, but
early diagnosis and monitoring can help prevent and treat such diseases. However, current …

Measurement of homocysteine: a historical perspective

SF Alam, S Kumar, P Ganguly - Journal of clinical biochemistry and …, 2019 - jstage.jst.go.jp
抄録 Elevated plasma level of homocysteine is being increasingly associated with many
diseases. There is a significant interest in the development of methods to determine the total …

Specific postcolumn detection method for HPLC assay of homocysteine based on aggregation of fluorosurfactant-capped gold nanoparticles

C Lu, Y Zu, VWW Yam - Analytical chemistry, 2007 - ACS Publications
Gold nanoparticles (GNPs) capped with nonionic fluorosurfactant molecules (Zonyl FSN)
were synthesized, and with the colloidal solution as a probe reagent, a new postcolumn …

Measurement of homocysteine and related metabolites in human plasma and urine by liquid chromatography electrospray tandem mass spectrometry

M Rafii, R Elango, JD House, G Courtney-Martin… - … of Chromatography B, 2009 - Elsevier
The sulfur amino acids, methionine and cysteine play crucial roles in cells as a substrate for
protein synthesis, as a methyl donor, and for the synthesis of sulfur-containing compounds …

Detection of homocysteine by conventional and microchip capillary electrophoresis/electrochemistry

SA Pasas, NA Lacher, MI Davies, SM Lunte - Electrophoresis, 2002 - Wiley Online Library
A method based on capillary electrophoresis (CE) with electrochemical (EC) detection for
the determination of both total homocysteine (tHcy) and protein‐bound homocysteine …

Homocysteine, endothelial dysfunction and oxidative stress in type 1 diabetes mellitus

F Wotherspoon, DW Laight, KM Shaw… - The British Journal …, 2003 - journals.sagepub.com
Type 1 diabetes is associated with an increased risk of cardiovascular disease, which
cannot be fully explained by traditional risk factors. Elevated plasma homocysteine is an …

Methods for measurements of oxidized LDL, homocysteine and nitric oxide as clinical parameters of oxidative stress and endothelial dysfunction

MT Macvanin, J Stanimirovic… - Current Analytical …, 2022 - ingentaconnect.com
Timely and accurate evaluation of clinical parameters associated with endothelial
dysfunction is critical in diagnosing and treating atherosclerosis, which represents a severe …