In silico models of aerosol delivery to the respiratory tract—development and applications

PW Longest, LT Holbrook - Advanced drug delivery reviews, 2012 - Elsevier
This review discusses the application of computational models to simulate the transport and
deposition of inhaled pharmaceutical aerosols from the site of particle or droplet formation to …

Role of CFD based in silico modelling in establishing an in vitro-in vivo correlation of aerosol deposition in the respiratory tract

F Huang, Q Zhu, X Zhou, D Gou, J Yu, R Li… - Advanced drug delivery …, 2021 - Elsevier
Effective evaluation and prediction of aerosol transport deposition in the human respiratory
tracts are critical to aerosol drug delivery and evaluation of inhalation products …

Computational analysis of aerosol-dynamics in a human whole-lung airway model

AV Kolanjiyil, C Kleinstreuer - Journal of Aerosol Science, 2017 - Elsevier
Prediction of the air-particle dynamics in human lungs can reveal critical deposition sites of
toxins or can determine best physical parameters for direct drug delivery and associated …

Characterization of nanomaterials for toxicity assessment

CM Sayes, DB Warheit - Wiley Interdisciplinary Reviews …, 2009 - Wiley Online Library
A key element of any nanomaterial toxicity screening strategy is a detailed and
comprehensive physicochemical characterization of the test material being studied. This is a …

Effectiveness of direct Lagrangian tracking models for simulating nanoparticle deposition in the upper airways

PW Longest, J Xi - Aerosol Science and Technology, 2007 - Taylor & Francis
Direct Lagrangian particle tracking may provide an effective method for simulating the
deposition of ultrafine aerosols in the upper respiratory airways that can account for finite …

Effects of mesh style and grid convergence on particle deposition in bifurcating airway models with comparisons to experimental data

PW Longest, S Vinchurkar - Medical engineering & physics, 2007 - Elsevier
A number of research studies have employed a wide variety of mesh styles and levels of grid
convergence to assess velocity fields and particle deposition patterns in models of …

Particokinetics and extrapulmonary translocation of intratracheally instilled ferric oxide nanoparticles in rats and the potential health risk assessment

MT Zhu, WY Feng, Y Wang, B Wang… - Toxicological …, 2009 - academic.oup.com
Exposure to nanoparticles has presented potential risks to human cardiorespiratory systems.
Pulmonary retention and extrapulmonary redistribution of inhaled nanoparticles have been …

Comparative computational modeling of airflows and vapor dosimetry in the respiratory tracts of rat, monkey, and human

RA Corley, S Kabilan, AP Kuprat… - Toxicological …, 2012 - academic.oup.com
Computational fluid dynamics (CFD) models are useful for predicting site-specific dosimetry
of airborne materials in the respiratory tract and elucidating the importance of species …

Study of lead phytoavailability for atmospheric industrial micronic and sub-micronic particles in relation with lead speciation

G Uzu, S Sobanska, Y Aliouane, P Pradere… - Environmental …, 2009 - Elsevier
Particles from channelled emissions of a battery recycling facility were size-segregated and
investigated to correlate their speciation and morphology with their transfer towards lettuce …

Measurement of metal bioaccessibility in vegetables to improve human exposure assessments: field study of soil–plant–atmosphere transfers in urban areas, South …

TT Xiong, C Dumat, A Pierart, M Shahid, Y Kang… - … geochemistry and health, 2016 - Springer
The quality of cultivated consumed vegetables in relation to environmental pollution is a
crucial issue for urban and peri-urban areas, which host the majority of people at the global …