Pain is a hallmark of tissue injury, inflammatory diseases, pathogen invasion and
neuropathy. It is mediated by nociceptor sensory neurons that innervate the skin, joints …

Nociceptor sensory neurons protect organisms from danger by eliciting pain and driving
avoidance. Pain also accompanies many types of inflammation and injury. It is increasingly …

The neuroanatomical basis behind acupuncture practice is still poorly understood. Here, we
used intersectional genetic strategy to ablate NPY+ noradrenergic neurons and/or adrenal …

Neuroimmunology is one of the fastest-growing fields in the life sciences, and for good
reason; it fills the gap between two principal systems of the organism, the nervous system …

Process of inflammation and complex interactions between immune and cancer cells within
tumor microenvironment are known to drive and shape the outcome of the neoplastic …

Introduction: Preclinical and clinical studies suggest that cannabidiol (CBD) found in
Cannabis spp. has broad therapeutic value. CBD products can currently be purchased …

Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide. Discovered 30
years ago, it is produced as a consequence of alternative RNA processing of the calcitonin …

Lung-innervating nociceptor sensory neurons detect noxious or harmful stimuli and
consequently protect organisms by mediating coughing, pain, and bronchoconstriction …

Nociceptor sensory neurons are specialized to detect potentially damaging stimuli,
protecting the organism by initiating the sensation of pain and eliciting defensive …

Evolution has yielded multiple complex and complementary mechanisms to detect
environmental danger and protect tissues from damage. The nervous system rapidly …