When host cells are exposed to foreign particles, dead cells, or cell hazards, a sophisticated
process called phagocytosis begins. During this process, macrophages, dendritic cells, and …

Plant-derived (poly) phenolic compounds have been undoubtedly shown to promote
endocrine homeostasis through the improvement of diverse metabolic outcomes. Amongst …

Transient receptor potential vanilloid 1 (TRPV1) is involved in sensory nerve nociceptive
signaling. Recently, it has been discovered that TRPV1 receptors also regulate basal body …

Timely initiation and termination of inflammatory response after corneal epithelial abrasion is
critical for the recovery of vision. The cornea is innervated with rich sensory nerves with …

Both sensory neurons and immune cells, albeit at markedly different levels, express the
vanilloid (capsaicin) receptor, Transient Receptor Potential, Vanilloid-1 (TRPV1). Activation …

Tissue injury, whether by trauma, surgical intervention, metabolic dysfunction, ischemia, or
infection, evokes a complex cellular response (inflammation) that is associated with painful …

Given the high rate of nonresponse or resistance to current inflammatory bowel disease
(IBD) treatments, novel drug targets and biomarkers that aid in therapeutic prediction are …

The transient receptor potential channel (TRP channel) family is a kind of non-specific cation
channel widely distributed in various tissues and organs of the human body, including the …

Sensing and responding to temperature is crucial in biology. The TRPV1 ion channel is a
well-studied heat-sensing receptor that is also activated by vanilloid compounds, including …

Although cannabinoids, such as Δ 9-tetrahydrocannabinol, have been studied extensively
for their psychoactive effects, it has become apparent that certain cannabinoids possess …