The role of transient receptor potential (TRP) channels in phagocytosis: a comprehensive review
MS Alavi, V Soheili, A Roohbakhsh - European Journal of Pharmacology, 2023 - Elsevier
When host cells are exposed to foreign particles, dead cells, or cell hazards, a sophisticated
process called phagocytosis begins. During this process, macrophages, dendritic cells, and …
process called phagocytosis begins. During this process, macrophages, dendritic cells, and …
[HTML][HTML] Plant-derived (poly) phenols and their metabolic outcomes: The pursuit of a role for the gut microbiota
Plant-derived (poly) phenolic compounds have been undoubtedly shown to promote
endocrine homeostasis through the improvement of diverse metabolic outcomes. Amongst …
endocrine homeostasis through the improvement of diverse metabolic outcomes. Amongst …
[HTML][HTML] The sympathetic nervous system is controlled by transient receptor potential vanilloid 1 in the regulation of body temperature
KM Alawi, AA Aubdool, L Liang, E Wilde… - The FASEB …, 2015 - ncbi.nlm.nih.gov
Transient receptor potential vanilloid 1 (TRPV1) is involved in sensory nerve nociceptive
signaling. Recently, it has been discovered that TRPV1 receptors also regulate basal body …
signaling. Recently, it has been discovered that TRPV1 receptors also regulate basal body …
[HTML][HTML] TRPV1+ sensory nerves modulate corneal inflammation after epithelial abrasion via RAMP1 and SSTR5 signaling
J Liu, S Huang, R Yu, X Chen, F Li, X Sun, P Xu… - Mucosal …, 2022 - Elsevier
Timely initiation and termination of inflammatory response after corneal epithelial abrasion is
critical for the recovery of vision. The cornea is innervated with rich sensory nerves with …
critical for the recovery of vision. The cornea is innervated with rich sensory nerves with …
[HTML][HTML] Carcinogenesis and metastasis: Focus on TRPV1-positive neurons and immune cells
N Erin, A Szallasi - Biomolecules, 2023 - mdpi.com
Both sensory neurons and immune cells, albeit at markedly different levels, express the
vanilloid (capsaicin) receptor, Transient Receptor Potential, Vanilloid-1 (TRPV1). Activation …
vanilloid (capsaicin) receptor, Transient Receptor Potential, Vanilloid-1 (TRPV1). Activation …
[HTML][HTML] Contemporary views on inflammatory pain mechanisms: TRPing over innate and microglial pathways
Z Guan, J Hellman, M Schumacher - F1000Research, 2016 - ncbi.nlm.nih.gov
Tissue injury, whether by trauma, surgical intervention, metabolic dysfunction, ischemia, or
infection, evokes a complex cellular response (inflammation) that is associated with painful …
infection, evokes a complex cellular response (inflammation) that is associated with painful …
TRP channels in inflammatory bowel disease: Potential therapeutic targets
Y Du, J Chen, L Shen, B Wang - Biochemical Pharmacology, 2022 - Elsevier
Given the high rate of nonresponse or resistance to current inflammatory bowel disease
(IBD) treatments, novel drug targets and biomarkers that aid in therapeutic prediction are …
(IBD) treatments, novel drug targets and biomarkers that aid in therapeutic prediction are …
[HTML][HTML] Function of TRP channels in monocytes/macrophages
J Wu, Z Li, Y Deng, X Lu, C Luo, X Mu, T Zhang… - Frontiers in …, 2023 - frontiersin.org
The transient receptor potential channel (TRP channel) family is a kind of non-specific cation
channel widely distributed in various tissues and organs of the human body, including the …
channel widely distributed in various tissues and organs of the human body, including the …
[HTML][HTML] Evidence that the TRPV1 S1-S4 membrane domain contributes to thermosensing
Sensing and responding to temperature is crucial in biology. The TRPV1 ion channel is a
well-studied heat-sensing receptor that is also activated by vanilloid compounds, including …
well-studied heat-sensing receptor that is also activated by vanilloid compounds, including …
[HTML][HTML] The endocannabinoid/endovanilloid N-arachidonoyl dopamine (NADA) and synthetic cannabinoid WIN55, 212-2 abate the inflammatory activation of human …
K Wilhelmsen, S Khakpour, A Tran, K Sheehan… - Journal of Biological …, 2014 - ASBMB
Although cannabinoids, such as Δ 9-tetrahydrocannabinol, have been studied extensively
for their psychoactive effects, it has become apparent that certain cannabinoids possess …
for their psychoactive effects, it has become apparent that certain cannabinoids possess …