[HTML][HTML] N-arachidonoyl dopamine modulates acute systemic inflammation via nonhematopoietic TRPV1
SK Lawton, F Xu, A Tran, E Wong… - The Journal of …, 2017 - journals.aai.org
N-Arachidonoyl dopamine (NADA) is an endogenous lipid that potently activates the
transient receptor potential vanilloid 1 (TRPV1), which mediates pain and thermosensation …
transient receptor potential vanilloid 1 (TRPV1), which mediates pain and thermosensation …
The Role of TRP Channels in Sepsis and Colitis
KA Dvornikova, ON Platonova, EY Bystrova - International Journal of …, 2024 - mdpi.com
To date, several members of the transient receptor potential (TRP) channels which provide a
wide array of roles have been found in the gastrointestinal tract (GI). The goal of earlier …
wide array of roles have been found in the gastrointestinal tract (GI). The goal of earlier …
Role of Kynurenine and Its Derivatives in the Neuroimmune System
M Fujikawa, M Ueda, K Maruyama - International Journal of Molecular …, 2024 - mdpi.com
In recent years, there has been a growing realization of intricate interactions between the
nervous and immune systems, characterized by shared humoral factors and receptors. This …
nervous and immune systems, characterized by shared humoral factors and receptors. This …
Endogenously generated arachidonate‐derived ligands for TRPV1 induce cardiac protection in sepsis
J Chen, AJP Hamers, M Finsterbusch… - The FASEB …, 2018 - Wiley Online Library
The severity of cardiac dysfunction predicts mortality in sepsis. Activation of transient
receptor potential vanilloid receptor type (TRPV)‐1, a predominantly neuronal nonselective …
receptor potential vanilloid receptor type (TRPV)‐1, a predominantly neuronal nonselective …
Transient receptor potential vanilloid 1 is expressed in human cytotrophoblasts: induction of cell apoptosis and impairment of syncytialization
MA Costa, BM Fonseca, E Keating, NA Teixeira… - The international journal …, 2014 - Elsevier
The normal development of placenta relies essentially on a balanced proliferation,
differentiation and apoptosis of cytotrophoblasts. These processes are tightly regulated by …
differentiation and apoptosis of cytotrophoblasts. These processes are tightly regulated by …
Nitric oxide donor protects against acetic acid-induced gastric ulcer in rats via S-nitrosylation of TRPV1 on vagus nerve
T Han, Y Tang, J Li, B Xue, L Gong, J Li, X Yu, C Liu - Scientific reports, 2017 - nature.com
This study was conducted to investigate the effects of nitric oxide (NO) in acetic acid-induced
gastric ulcer of rats and the underlying mechanisms. We found that peritoneal injection of …
gastric ulcer of rats and the underlying mechanisms. We found that peritoneal injection of …
Radiosensitizing effect of TRPV1 channel inhibitors in cancer cells
K Nishino, K Tanamachi, Y Nakanishi, S Ide… - Biological and …, 2016 - jstage.jst.go.jp
Radiosensitizers are used in cancer therapy to increase the γ-irradiation susceptibility of
cancer cells, including radioresistant hypoxic cancer cells within solid tumors, so that …
cancer cells, including radioresistant hypoxic cancer cells within solid tumors, so that …
TRPV1 and SP: key elements for sepsis outcome?
JV Bodkin, ES Fernandes - British journal of pharmacology, 2013 - Wiley Online Library
Sensory neurons play important roles in many disorders, including inflammatory diseases,
such as sepsis. Sepsis is a potentially lethal systemic inflammatory reaction to a local …
such as sepsis. Sepsis is a potentially lethal systemic inflammatory reaction to a local …
Immune aspects of the bi-directional neuroimmune facilitator TRPV1
A rapidly growing area of interest in biomedical science involves the reciprocal crosstalk
between the sensory nervous and immune systems. Both of these systems are highly …
between the sensory nervous and immune systems. Both of these systems are highly …
Transient receptor potential vanilloid 1 inhibitors block laparotomy‐and opioid‐induced infarct size reduction in rats
HM Heymann, Y Wu, Y Lu, N Qvit… - British Journal of …, 2017 - Wiley Online Library
Background and Purpose In light of the opioid epidemic, physicians are increasingly
prescribing non‐opioid analgesics to surgical patients. Transient receptor potential vanilloid …
prescribing non‐opioid analgesics to surgical patients. Transient receptor potential vanilloid …