Natural products targeting tumour angiogenesis
Tumour angiogenesis is the formation of new blood vessels to support the growth of a
tumour. This process is critical for tumour progression and metastasis, making it an attractive …
tumour. This process is critical for tumour progression and metastasis, making it an attractive …
Targeting lipid metabolism with natural products: A novel strategy for gastrointestinal cancer therapy
C Guo, L Zhang, M Zhao, Y Ai, W Liao… - Phytotherapy …, 2023 - Wiley Online Library
Gastrointestinal cancer (GIC), including gastric cancer and colorectal cancer, is a common
malignant tumor originating from gastrointestinal epithelial cells. Although the pathogenesis …
malignant tumor originating from gastrointestinal epithelial cells. Although the pathogenesis …
[HTML][HTML] Mechanistic inhibition of gastric cancer-associated bacteria Helicobacter pylori by selected phytocompounds: A new cutting-edge computational approach
Background Helicobacter pylori (H. pylori) is a persistent bacterial inhabitant in the stomachs
of approximately half the global populace. This bacterium is directly linked to chronic …
of approximately half the global populace. This bacterium is directly linked to chronic …
[HTML][HTML] Harnessing the power of traditional Chinese medicine monomers and compound prescriptions to boost cancer immunotherapy
K Miao, W Liu, J Xu, Z Qian, Q Zhang - Frontiers in immunology, 2023 - frontiersin.org
At present, cancer is the largest culprit that endangers human health. The current treatment
options for cancer mainly include surgical resection, adjuvant radiotherapy and …
options for cancer mainly include surgical resection, adjuvant radiotherapy and …
Dihydroartemisinin inhibits the development of colorectal cancer by GSK-3β/TCF7/MMP9 pathway and synergies with capecitabine
X Dai, W Chen, Y Qiao, X Chen, Y Chen, K Zhang… - Cancer Letters, 2024 - Elsevier
Patients with colorectal cancer (CRC) suffer from poor prognosis and lack effective drugs.
Dihydroartemisinin (DHA) has anti-cancer potential but the mechanism remains unclear. We …
Dihydroartemisinin (DHA) has anti-cancer potential but the mechanism remains unclear. We …
[HTML][HTML] Ten years of research on fucoidan and cancer: Focus on its antiangiogenic and antimetastatic effects
E Turrini, F Maffei, C Fimognari - Marine Drugs, 2023 - mdpi.com
Angiogenesis and metastasis represent two challenging targets to combat cancer
development in the later stages of its progression. Numerous studies have indicated the …
development in the later stages of its progression. Numerous studies have indicated the …
Synergistic therapeutic strategies and engineered nanoparticles for anti-vascular endothelial growth factor therapy in cancer
Angiogenesis is one of the defining characteristics of cancer. Vascular endothelial growth
factor (VEGF) is crucial for the development of angiogenesis. A growing interest in cancer …
factor (VEGF) is crucial for the development of angiogenesis. A growing interest in cancer …
Natural products for gastric carcinoma prevention and treatment: focus on their antioxidant stress actions in the Correa's cascade
C Guo, L Wan, C Li, Y Wen, H Pan, M Zhao, J Wang… - Phytomedicine, 2023 - Elsevier
Background Correa's cascade is a pathological process beginning from gastritis to gastric
precancerous lesions, and finally to gastric carcinoma (GC). While the pathogenesis of GC …
precancerous lesions, and finally to gastric carcinoma (GC). While the pathogenesis of GC …
Network Pharmacology and Experimental Validation to Explore the Potential Mechanism of Nigella sativa for the Treatment of Breast Cancer
Breast cancer is a prevalent and potentially life-threatening disease that affects women
worldwide. Natural products have gained attention as potential anticancer agents due to …
worldwide. Natural products have gained attention as potential anticancer agents due to …
Pachymic acid activates TP53INP2/TRAF6/caspase‐8 pathway to promote apoptosis in renal cell carcinoma cells
X Li, A He, C Liu, Y Li, Y Luo, W Xiong… - Environmental …, 2024 - Wiley Online Library
While pachymic acid (PA), a key component of Poria cocos (Schw.), has demonstrated anti‐
tumor effects in lung, breast, and pancreatic cancers, its impact on renal cell carcinoma …
tumor effects in lung, breast, and pancreatic cancers, its impact on renal cell carcinoma …