[HTML][HTML] Analytical techniques in pharmaceutical analysis: A review

MR Siddiqui, ZA AlOthman, N Rahman - Arabian Journal of chemistry, 2017 - Elsevier
The development of the pharmaceuticals brought a revolution in human health. These
pharmaceuticals would serve their intent only if they are free from impurities and are …

[HTML][HTML] Matrix-assisted laser desorption ionization time-of-flight mass spectrometry in clinical microbiology: what are the current issues?

A Van Belkum, M Welker, D Pincus… - Annals of laboratory …, 2017 - ncbi.nlm.nih.gov
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS)
has revolutionized the identification of microbial species in clinical microbiology …

A rapid matrix-assisted laser desorption ionization–time of flight mass spectrometry-based method for single-plasmid tracking in an outbreak of carbapenem-resistant …

AF Lau, H Wang, RA Weingarten… - Journal of clinical …, 2014 - Am Soc Microbiol
Carbapenem-resistant Enterobacteriaceae (CRE) have spread globally and represent a
serious and growing threat to public health. Rapid methods for tracking plasmids carrying …

[HTML][HTML] Proteomics as a tool for studying bacterial virulence and antimicrobial resistance

FJ Pérez-Llarena, G Bou - Frontiers in microbiology, 2016 - frontiersin.org
Proteomic studies have improved our understanding of the microbial world. The most recent
advances in this field have helped us to explore aspects beyond genomics. For example, by …

Current methods for the identification of carbapenemases

AZ Bialvaei, HS Kafil, M Asgharzadeh… - Journal of …, 2016 - Taylor & Francis
Detection of carbapenemases in clinical microbiology labs is a challenging issue.
Comparison of the results of susceptibility testing with the breakpoint values of carbapenems …

[HTML][HTML] One system for all: is mass spectrometry a future alternative for conventional antibiotic susceptibility testing?

M Welker, A Van Belkum - Frontiers in microbiology, 2019 - frontiersin.org
The two main pillars of clinical microbiological diagnostics are the identification of potentially
pathogenic microorganisms from patient samples and the testing for antibiotic susceptibility …

[HTML][HTML] Clinical mass spectrometry in the bioinformatics era: a Hitchhiker's guide

YK Chong, CC Ho, SY Leung, SKP Lau… - Computational and …, 2018 - Elsevier
Mass spectrometry (MS) is a sensitive, specific and versatile analytical technique in the
clinical laboratory that has recently undergone rapid development. From initial use in …

Novel strategies for rapid identification and susceptibility testing of MRSA

M Mizusawa, KC Carroll - Expert Review of Anti-infective Therapy, 2020 - Taylor & Francis
ABSTRACT Introduction Methicillin-resistant Staphylococcus aureus (MRSA) is associated
with adverse clinical outcomes and increased morbidity, mortality, length of hospital stay …

Investigations on antimicrobial activity of cobaltabisdicarbollides

T Popova, A Zaulet, F Teixidor, R Alexandrova… - Journal of …, 2013 - Elsevier
Metallacarboranes have been identified as promising pharmacophores and building blocks
in drug designed as well as inhibitors of HIV. The aim of this study was to evaluate the …

[HTML][HTML] Peptide markers for rapid detection of KPC carbapenemase by LC-MS/MS

H Wang, SK Drake, JH Youn, AZ Rosenberg, Y Chen… - Scientific reports, 2017 - nature.com
Carbapenemase producing organisms (CPOs) represent an urgent public health threat, and
the need for new rapid methods to detect these organisms has been widely recognized …