[HTML][HTML] New tendencies in non-surgical periodontal therapy
AN Haas, F Furlaneto, EJ Gaio, SC Gomes… - Brazilian oral …, 2021 - SciELO Brasil
The aim of this review was to update the evidence of new approaches to non-surgical
therapy (NSPT) in the treatment of periodontitis. Preclinical and clinical studies addressing …
therapy (NSPT) in the treatment of periodontitis. Preclinical and clinical studies addressing …
Contribution of statins towards periodontal treatment: a review
C Petit, F Batool, IM Bugueno, P Schwinté… - Mediators of …, 2019 - Wiley Online Library
The pleiotropic effects of statins have been evaluated to assess their potential benefit in the
treatment of various inflammatory and immune‐mediated diseases including periodontitis …
treatment of various inflammatory and immune‐mediated diseases including periodontitis …
[HTML][HTML] The effects of statins on dental and oral health: a review of preclinical and clinical studies
The statin family of drugs are safe and effective therapeutic agents for the treatment of
arteriosclerotic cardiovascular disease (CVD). Due to a wide range of health benefits in …
arteriosclerotic cardiovascular disease (CVD). Due to a wide range of health benefits in …
[HTML][HTML] IL-6 induced by periodontal inflammation causes neuroinflammation and disrupts the blood–brain barrier
D Furutama, S Matsuda, Y Yamawaki, S Hatano… - Brain Sciences, 2020 - mdpi.com
Background: Periodontal disease (PD) is a risk factor for systemic diseases, including
neurodegenerative diseases. The role of the local and systemic inflammation induced by PD …
neurodegenerative diseases. The role of the local and systemic inflammation induced by PD …
Periodontitis and endothelial dysfunction: Periodontal clinical parameters and levels of salivary markers interleukin‐1β, tumor necrosis factor‐α, matrix …
MF Moura, TP Navarro, TA Silva… - Journal of …, 2017 - Wiley Online Library
Background: Periodontitis has been associated with a greater risk for atherosclerotic
cardiovascular disease (ACD). Endothelial dysfunction (ED) is a parameter of early ACD …
cardiovascular disease (ACD). Endothelial dysfunction (ED) is a parameter of early ACD …
Statins in nonsurgical and surgical periodontal therapy. A systematic review and meta‐analysis of preclinical in vivo trials
K Bertl, I Steiner, N Pandis, K Buhlin… - Journal of …, 2018 - Wiley Online Library
The cholesterol‐lowering drugs, statins, possess anti‐inflammatory, antimicrobial and pro‐
osteogenic properties, and thus have been tested as an adjunct to periodontal treatment …
osteogenic properties, and thus have been tested as an adjunct to periodontal treatment …
Effects of Systemic Simvastatin on the Concentrations of Visfatin, Tumor Necrosis Factor‐α, and Interleukin‐6 in Gingival Crevicular Fluid in Patients with Type 2 …
MA Bahammam, MS Attia - Journal of immunology research, 2018 - Wiley Online Library
Purpose. The objective of this study is to explore the relationship between the levels of
interleukin‐(IL‐) 6, tumor necrosis factor‐(TNF‐) α, and visfatin and simvastatin usage, in the …
interleukin‐(IL‐) 6, tumor necrosis factor‐(TNF‐) α, and visfatin and simvastatin usage, in the …
Statins with potential to control periodontitis: From biological mechanisms to clinical studies
RDP de Carvalho, RCV Casarin, PO de Lima… - Journal of Oral …, 2021 - Elsevier
Background Statins are widely used for the treatment of hyperlipidemia. However, these
drugs have pleiotropic effects that can be promising for the prevention and treatment of oral …
drugs have pleiotropic effects that can be promising for the prevention and treatment of oral …
Effect of 1.2% of simvastatin gel as a local drug delivery system on Gingival Crevicular Fluid interleukin-6 & interleukin-8 levels in non surgical treatment of chronic …
GG Vemanaradhya, S Emani, DS Mehta… - Archives of Oral …, 2017 - Elsevier
Aim The present study was carried out to evaluate the effect of 1.2% simvastatin gel as local
drug delivery (LDD) system on Gingival Crevicular Fluid (GCF) Interleukin-6 (IL-6) and …
drug delivery (LDD) system on Gingival Crevicular Fluid (GCF) Interleukin-6 (IL-6) and …
[HTML][HTML] Endothelial dysfunction in rats with ligature-induced periodontitis: Participation of nitric oxide and cycloxygenase-2-derived products
P Campi, BS Herrera, FN de Jesus, M Napolitano… - Archives of Oral …, 2016 - Elsevier
Objectives Considering the evident relationship between periodontitis and cardiovascular
diseases in humans, we aimed to study the in vitro vascular reactivity of aorta rings prepared …
diseases in humans, we aimed to study the in vitro vascular reactivity of aorta rings prepared …