Significance of chimerism in hematopoietic stem cell transplantation: new variations on an old theme

F Khan, A Agarwal, S Agrawal - Bone marrow transplantation, 2004 - nature.com
The main goal of post-transplantation monitoring in hematopoietic stem cell transplantation
(HSCT) is to predict negative events, such as disease relapse, graft rejection and graft …

Chimerism analysis for clinicians: a review of the literature and worldwide practices

AG Blouin, M Askar - Bone marrow transplantation, 2022 - nature.com
This review highlights literature pertinent to chimerism analysis in the context of
hematopoietic cell transplantation (HCT). We also conducted a survey of testing practices of …

Quantitative assessment of hematopoietic chimerism after bone marrow transplantation by real-time quantitative polymerase chain reaction

M Alizadeh, M Bernard, B Danic… - Blood, The Journal …, 2002 - ashpublications.org
We have developed a real-time quantitative polymerase chain reaction (PCR) assay using
TaqMan technology (Applied Biosystems, Foster City, CA) for monitoring donor cell …

Studies of FLT3 mutations in paired presentation and relapse samples from patients with acute myeloid leukemia: implications for the role of FLT3 mutations in …

PD Kottaridis, RE Gale, SE Langabeer… - Blood, The Journal …, 2002 - ashpublications.org
FLT3 mutations, either internal tandem duplications (ITDs) or aspartate residue 835 (D835)
point mutations, are present in approximately one third of patients with acute myeloid …

Limiting transplantation-related mortality following unrelated donor stem cell transplantation by using a nonmyeloablative conditioning regimen

R Chakraverty, K Peggs, R Chopra… - Blood, The Journal …, 2002 - ashpublications.org
A nonmyeloablative conditioning regimen was investigated in 47 patients with
hematological malignancy receiving allogeneic progenitor cells from matched, unrelated …

Quantitative analysis of chimerism after allogeneic stem cell transplantation by real‐time polymerase chain reaction with single nucleotide polymorphisms, standard …

M Koldehoff, NK Steckel, M Hlinka… - American journal of …, 2006 - Wiley Online Library
We compared the results of chimerism analyses with real‐time SNP‐PCR to those obtained
by the classical STR‐PCR method in 135 hematopoietic stem cell transplantation recipients …

Reduced-intensity conditioning followed by allografting of hematopoietic cells can produce clinical and molecular remissions in patients with poor-risk hematologic …

P Corradini, C Tarella, A Olivieri… - Blood, The Journal …, 2002 - ashpublications.org
A reduced-intensity conditioning regimen was investigated in 45 patients with hematologic
malignancies who were considered poor candidates for conventional myeloablative …

Chimerism status is a useful predictor of relapse after allogeneic stem cell transplantation for acute leukemia

M Barrios, A Jiménez-Velasco, J Román-Gómez… - …, 2003 - haematologica.org
BACKGROUND AND OBJECTIVES: The role of hematopoietic chimerism after allogeneic
stem cell transplantation (SCT) for acute leukemia remains controversial. We studied the …

Early detection of BCR-ABL transcripts by quantitative reverse transcriptase–polymerase chain reaction predicts outcome after allogeneic stem cell transplantation for …

E Olavarria, E Kanfer, R Szydlo, J Kaeda… - Blood, The Journal …, 2001 - ashpublications.org
The reverse transcriptase–polymerase chain reaction (RT-PCR) has become widely used
for monitoring minimal residual disease after allogeneic stem cell transplantation (SCT) for …

[HTML][HTML] Retrospective, landmark analysis of long-term adult morbidity following allogeneic HSCT for inborn errors of immunity in infancy and childhood

JW Day, R Elfeky, B Nicholson, R Goodman… - Journal of Clinical …, 2022 - Springer
Purpose Allogeneic hematopoietic stem cell transplant (HSCT) remains the treatment of
choice for patients with inborn errors of immunity (IEI). There is little published medical …