Increasing mixed chimerism (MC) after allogeneic stem cell transplantation (SCT) has been
associated with a high risk of relapse in acute leukemia. We evaluated a new method for …

The aim of this study was to evaluate the performance of a novel NGS-based assay to
monitor mixed chimerism (MC) and compare its technical capacity to established techniques …

Abstract Analysis of donor chimerism has become a routine method for the documentation of
engraftment after allogeneic hematopoietic stem cell transplantation (HSCT). In recent years …

Relapse has become the major cause of treatment failure after allogeneic stem cell
transplantation. Outcome of patients with clinical relapse after transplantation generally …

Purpose In the era of molecular therapy of chronic myelogenous leukemia (CML) applying
BCR-ABL tyrosine kinase inhibitors, the usefulness of molecular end points, in particular …

In this study, we used multiparameter flow cytometry to quantify minimal residual disease
(MRD) in 165 serial bone marrow samples from 40 patients diagnosed with acute …

BACKGROUND Neutrophilic‐chronic myeloid leukemia (CML‐N) has been described as a
CML variant associated both with a distinctive molecular defect of the Philadelphia …

Graft‐versus‐host disease (GVHD) is still a major complication after allogeneic stem cell
transplantation. In murine models, freshly isolated or ex vivo expanded CD4+ CD25high …

Purpose Allogeneic hematopoietic stem cell transplant (HSCT) remains the treatment of
choice for patients with inborn errors of immunity (IEI). There is little published medical …

Chronic myeloid leukemia provides an illustrative disease model for both molecular
pathogenesis of cancer and rational drug therapy. Chronic myeloid leukemia is a clonal …