Precise nanomedicine for intelligent therapy of cancer

H Chen, Z Gu, H An, C Chen, J Chen, R Cui… - Science China …, 2018 - Springer
Precise nanomedicine has been extensively explored for efficient cancer imaging and
targeted cancer therapy, as evidenced by a few breakthroughs in their preclinical and …

Chemical design and synthesis of functionalized probes for imaging and treating tumor hypoxia

J Liu, W Bu, J Shi - Chemical reviews, 2017 - ACS Publications
Hypoxia development in tumor is closely associated with its increased aggressiveness and
strong resistance to therapy, leading to the poor prognosis in several cancer types …

Rational design of bisphosphonate lipid-like materials for mRNA delivery to the bone microenvironment

L Xue, N Gong, SJ Shepherd, X Xiong… - Journal of the …, 2022 - ACS Publications
The development of lipid nanoparticle (LNP) formulations for targeting the bone
microenvironment holds significant potential for nucleic acid therapeutic applications …

Lipid-based DNA therapeutics: hallmarks of non-viral gene delivery

J Buck, P Grossen, PR Cullis, J Huwyler… - ACS …, 2019 - ACS Publications
Gene therapy is a promising strategy for the treatment of monogenic disorders. Non-viral
gene delivery systems including lipid-based DNA therapeutics offer the opportunity to …

[HTML][HTML] A review on graphene-based nanomaterials in biomedical applications and risks in environment and health

TP Dasari Shareena, D McShan, AK Dasmahapatra… - Nano-micro letters, 2018 - Springer
Graphene-based nanomaterials (GBNs) have attracted increasing interests of the scientific
community due to their unique physicochemical properties and their applications in …

“Combo” nanomedicine: co-delivery of multi-modal therapeutics for efficient, targeted, and safe cancer therapy

JA Kemp, MS Shim, CY Heo, YJ Kwon - Advanced drug delivery reviews, 2016 - Elsevier
The dynamic and versatile nature of diseases such as cancer has been a pivotal challenge
for developing efficient and safe therapies. Cancer treatments using a single therapeutic …

Genetically Engineered‐Cell‐Membrane Nanovesicles for Cancer Immunotherapy

Q Cheng, Y Kang, B Yao, J Dong, Y Zhu… - Advanced …, 2023 - Wiley Online Library
The advent of immunotherapy has marked a new era in cancer treatment, offering significant
clinical benefits. Cell membrane as drug delivery materials has played a crucial role in …

Functional supramolecular polymers for biomedical applications

R Dong, Y Zhou, X Huang, X Zhu, Y Lu… - Advanced …, 2015 - Wiley Online Library
As a novel class of dynamic and non‐covalent polymers, supramolecular polymers not only
display specific structural and physicochemical properties, but also have the ability to …

Engineered exosome-mediated delivery of functionally active miR-26a and its enhanced suppression effect in HepG2 cells

G Liang, S Kan, Y Zhu, S Feng, W Feng… - International journal of …, 2018 - Taylor & Francis
Introduction Exosomes are closed-membrane nanovesicles that are secreted by a variety of
cells and exist in most body fluids. Recent studies have demonstrated the potential of …

Theranostics: combining imaging and therapy

SS Kelkar, TM Reineke - Bioconjugate chemistry, 2011 - ACS Publications
Employing theranostic nanoparticles, which combine both therapeutic and diagnostic
capabilities in one dose, has promise to propel the biomedical field toward personalized …