Peripheral neuropathies are characterized by nerves damage and axonal loss, and they
could be classified in hereditary or acquired forms. Acquired peripheral neuropathies are …

Taxanes, mainly paclitaxel and docetaxel, the microtubule stabilizers, have been well known
for being the first-line therapy for breast cancer for more than the last thirty years. Moreover …

Simple Summary Chemotherapy-induced peripheral neuropathy (CIPN) is a common and
persistent complication of commonly used chemotherapy drugs. This article provides an …

Opioids are employed in the management of chemotherapy-induced neuropathic pain
(CINP) when other pain management approaches have failed and proven ineffective …

Glia are critical players in defining synaptic contacts and maintaining neuronal homeostasis.
Both astrocytes as glia of the central nervous system (CNS), as well as satellite glial cells …

Chemotherapy‐induced peripheral neuropathy (CIPN) is a common dose‐limiting toxicity
that affects 30%–40% of patients undergoing cancer treatment. Although multiple …

Background Paclitaxel is a taxane-based chemotherapeutic agent used as a treatment in
breast cancer. There is no effective prevention or treatment strategy for the most common …

Introduction Paclitaxel is a chemotherapy drug that is commonly used to treat cancer, but it
can cause paclitaxel-induced neuropathic pain (PINP) as a side effect. Resolvin D1 (RvD1) …

Introduction Chemotherapy-induced polyneuropathy (CIPN) and post-chemotherapy
cognitive impairment (PCCI) are frequent side effects of paclitaxel treatment. CIPN/PCCI are …

Background Mounting evidence suggests that the immune system plays detrimental or
protective roles in nerve injury and repair. Main body Herein we report that both …