Mitochondria-targeted triphenylphosphonium-based compounds: syntheses, mechanisms of action, and therapeutic and diagnostic applications
Mitochondria are recognized as one of the most important targets for new drug design in
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …
Photodynamic therapy: Innovative approaches for antibacterial and anticancer treatments
M Kolarikova, B Hosikova, H Dilenko… - Medicinal Research …, 2023 - Wiley Online Library
Photodynamic therapy is an alternative treatment mainly for cancer but also for bacterial
infections. This treatment dates back to 1900 when a German medical school graduate …
infections. This treatment dates back to 1900 when a German medical school graduate …
Piezocatalytic 2D WS2 Nanosheets for Ultrasound‐Triggered and Mitochondria‐Targeted Piezodynamic Cancer Therapy Synergized with Energy Metabolism …
Q Truong Hoang, KA Huynh… - Advanced …, 2023 - Wiley Online Library
Piezoelectric nanomaterials that can generate reactive oxygen species (ROS) by
piezoelectric polarization under an external mechanical force have emerged as an effective …
piezoelectric polarization under an external mechanical force have emerged as an effective …
Mitochondrion-specific dendritic lipopeptide liposomes for targeted sub-cellular delivery
The mitochondrion is an important sub-cellular organelle responsible for the cellular
energetic source and processes. Owing to its unique sensitivity to heat and reactive oxygen …
energetic source and processes. Owing to its unique sensitivity to heat and reactive oxygen …
Tumor abnormality-oriented nanomedicine design
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
Organelle-targeted therapies: a comprehensive review on system design for enabling precision oncology
Cancer is a major threat to human health. Among various treatment methods, precision
therapy has received significant attention since the inception, due to its ability to efficiently …
therapy has received significant attention since the inception, due to its ability to efficiently …
[HTML][HTML] Mitochondria-targeting drug conjugates for cytotoxic, anti-oxidizing and sensing purposes: current strategies and future perspectives
G Battogtokh, YS Choi, DS Kang, SJ Park… - … Pharmaceutica Sinica B, 2018 - Elsevier
Mitochondrial targeting is a promising approach for solving current issues in clinical
application of chemotherapy and diagnosis of several disorders. Here, we discuss direct …
application of chemotherapy and diagnosis of several disorders. Here, we discuss direct …
Multifunctional nanoplatforms for subcellular delivery of drugs in cancer therapy
To achieve highly effective treatment to diseases, successful delivery of drugs with a carrier
into the specific organelles (nucleus, mitochondria, lysosomes, etc.) is of great importance …
into the specific organelles (nucleus, mitochondria, lysosomes, etc.) is of great importance …
Smart Design of Nanomaterials for Mitochondria‐Targeted Nanotherapeutics
Mitochondria are the powerhouse of cells. They are vital organelles that maintain cellular
function and metabolism. Dysfunction of mitochondria results in various diseases with a …
function and metabolism. Dysfunction of mitochondria results in various diseases with a …
Regulating Photosensitizer Metabolism with DNAzyme-Loaded Nanoparticles for Amplified Mitochondria-Targeting Photodynamic Immunotherapy
X Zhao, H Cheng, Q Wang, W Nie, Y Yang, X Yang… - ACS …, 2023 - ACS Publications
Mitochondria-specific photosensitizer accumulation is highly recommended for
photodynamic therapy and mitochondrial DNA (mtDNA) oxidative damage-based innate …
photodynamic therapy and mitochondrial DNA (mtDNA) oxidative damage-based innate …