Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
the loss of upper and lower motor neurons. Presently, three FDA-approved drugs are …

Alzheimer's disease (AD) is currently constrained by limited clinical treatment options. The
initial pathophysiological event, which can be traced back to decades before the clinical …

Alzheimer's disease (AD) is a complex and heterogeneous neurodegenerative disorder with
contributions from multiple pathophysiological pathways. One of the long-recognized and …

Alzheimer's disease (AD) is currently defined by the aggregation of amyloid-β (Aβ) and tau
proteins in the brain. Although biofluid biomarkers are available to measure Aβ and tau …

Alzheimer's disease (AD) diagnosis utilizing single modality neuroimaging data has
limitations. Multimodal fusion of complementary biomarkers may improve diagnostic …

Adults with Down syndrome have a genetic form of Alzheimer's disease (AD) and evidence
of cerebrovascular disease across the AD continuum, despite few systemic vascular risk …

Alzheimer's disease (AD) is currently defined at the research level by the aggregation of
amyloid-β (Aβ) and tau proteins in brain. While biofluid biomarkers are available to measure …

INTRODUCTION We examined the association of clinical, microbiological, and host
response features of periodontitis with MRI markers of atrophy/cerebrovascular disease in …

Dementia poses a substantial global health challenge, warranting an exploration of its
intricate pathophysiological mechanisms and potential intervention targets. Leveraging multi …

Alzheimer's disease (AD) and schizophrenia (SCZ) represent two major neuropathological
conditions with a high disease burden. Despite their distinct etiologies, patients suffering …