In the pharmaceutical industry, poorly water-soluble drugs require enabling technologies to
increase apparent solubility in the biological environment. Amorphous solid dispersion …

Driven by the new trend to build quality into products and reducing empiricism, small-scale
screening techniques have been frequently used to evaluate, thermodynamic of drug …

The present study evaluated the specific intermolecular interactions between
carbamazepine (CBZ) and substituents of hypromellose acetate succinate (HPMC-AS), as …

In the pharmaceutical industry, polymers are used as excipients for formulating poorly water-
soluble active pharmaceutical ingredients (APIs) in so-called “amorphous solid …

In this study, the molecular states of supersaturated drugs and crystallization inhibitors in
aqueous solutions were characterized using NMR to elucidate the inhibition mechanism of …

During the development of pharmaceutical spray-dried formulations, many samples must be
prepared for physico-chemical characterisation and dissolution testing by systematically …

Amorphous solid dispersions (ASDs), where the drug is dispersed in a polymer, have
become increasingly prevalent as a formulation strategy for the oral delivery of poorly …

The combined effect of solvent, cellulosic polymer, and a poorly water-soluble drug,
fenofibrate (FNB) on solution-cast pharmaceutical film quality attributes, eg, morphology …

We demonstrated a facile approach, by adjusting the solvent ratio of water/acetone binary
mixture, to alter the intermolecular interactions between Enzalutamide (ENZ) and …

Amorphization, typically in the form of amorphous solid dispersion (ASD), represents a well-
established solubility enhancement strategy for poorly soluble drugs. Recently, two …