Aims Pressure-wire assessment of coronary stenosis is considered the invasive reference
standard for detection of ischaemia-generating lesions. Recently, methods to estimate the …

Background Compared with visual angiographic assessment, pressure wire-based
physiological measurement more accurately identifies flow-limiting lesions in patients with …

All patients with stable ischemic heart disease (SIHD) should be managed with guideline-
directed medical therapy (GDMT), which reduces progression of atherosclerosis and …

The Japanese Circulation Society (JCS) published the “Guidelines for elective percutaneous
coronary intervention [PCI] in patients with stable coronary disease” in 2000. In 2006 …

Background—The use of coronary angiography (CA) for diagnosis and management of
chest pain (CP) has several flaws. The assessment of coronary artery disease using …

Aims: The aim of this study was to validate novel software to calculate vessel fractional flow
reserve (vFFR) based on 3D-QCA and to assess inter-observer variability in patients who …

Objectives: This study sought to evaluate the intravascular ultrasound (IVUS) minimal lumen
area (MLA) for functionally significant left main coronary artery (LMCA) stenosis using …

Background—There is no large report of the impact of fractional flow reserve (FFR) on the
reclassification of the coronary revascularization strategy on individual patients referred for …

Objectives: The aims of the present study were: 1) to investigate the contribution of the extent
of luminal stenosis and other lesion composition-related factors in predicting invasive …

Importance Obstructive coronary lesions with reduced luminal dimensions may result in
abnormal regional myocardial blood flow as assessed by stress-induced myocardial …