RNA‐binding proteins, neural development and the addictions
Transcriptional and post‐transcriptional regulation of gene expression defines the
neurobiological mechanisms that bridge genetic and environmental risk factors with …
neurobiological mechanisms that bridge genetic and environmental risk factors with …
Rare deleterious mutations of HNRNP genes result in shared neurodevelopmental disorders
Background With the increasing number of genomic sequencing studies, hundreds of genes
have been implicated in neurodevelopmental disorders (NDDs). The rate of gene discovery …
have been implicated in neurodevelopmental disorders (NDDs). The rate of gene discovery …
Respiration-deficient astrocytes survive as glycolytic cells in vivo
LM Supplie, T Düking, G Campbell, F Diaz… - Journal of …, 2017 - Soc Neuroscience
Neurons and glial cells exchange energy-rich metabolites and it has been suggested,
originally based on in vitro data, that astrocytes provide lactate to glutamatergic synapses …
originally based on in vitro data, that astrocytes provide lactate to glutamatergic synapses …
Imaging mRNA and protein interactions within neurons
C Eliscovich, SM Shenoy… - Proceedings of the …, 2017 - National Acad Sciences
RNA–protein interactions are essential for proper gene expression regulation, particularly in
neurons with unique spatial constraints. Currently, these interactions are defined …
neurons with unique spatial constraints. Currently, these interactions are defined …
Sorting mRNA molecules for cytoplasmic transport and localization
N Neriec, P Percipalle - Frontiers in Genetics, 2018 - frontiersin.org
In eukaryotic cells, gene expression is highly regulated at many layers. Nascent RNA
molecules are assembled into ribonucleoprotein complexes that are then released into the …
molecules are assembled into ribonucleoprotein complexes that are then released into the …
Axonal mRNA binding of hnRNP A/B is crucial for axon targeting and maturation of olfactory sensory neurons
N Fukuda, T Fukuda, P Percipalle, K Oda, N Takei… - Cell reports, 2023 - cell.com
Spatiotemporal control of gene expression is important for neural development and function.
Here, we show that heterogeneous nuclear ribonucleoprotein (hnRNP) A/B is highly …
Here, we show that heterogeneous nuclear ribonucleoprotein (hnRNP) A/B is highly …
Long non-coding RNA LncKdm2b regulates cortical neuronal differentiation by cis-activating Kdm2b
W Li, W Shen, B Zhang, K Tian, Y Li, L Mu, Z Luo… - Protein & …, 2020 - academic.oup.com
The mechanisms underlying spatial and temporal control of cortical neurogenesis of the
brain are largely elusive. Long non-coding RNAs (lncRNAs) have emerged as essential cell …
brain are largely elusive. Long non-coding RNAs (lncRNAs) have emerged as essential cell …
N-cadherin promotes recruitment and migration of neural progenitor cells from the SVZ neural stem cell niche into demyelinated lesions
Discrete cellular microenvironments regulate stem cell pools and their development, as well
as function in maintaining tissue homeostasis. Although the signaling elements modulating …
as function in maintaining tissue homeostasis. Although the signaling elements modulating …
The N6‐methyladenosine demethylase FTO is required for odontoblast differentiation in vitro and dentine formation in mice by promoting RUNX2 exon 5 inclusion …
M Xu, B Li, J Huang, R Jia, J Guo - International Endodontic …, 2023 - Wiley Online Library
Aim Fat mass and obesity‐associated (FTO) protein, the first discovered N6‐methyladenine
(m6A) demethylase, played positive roles in bone formation. In this study, the aim was to …
(m6A) demethylase, played positive roles in bone formation. In this study, the aim was to …
A conserved function in phosphatidylinositol metabolism for mammalian Vps13 family proteins
The Vps13 protein family is highly conserved in eukaryotic cells. In humans, mutations in the
gene encoding the family member VPS13A lead to the neurodegenerative disorder chorea …
gene encoding the family member VPS13A lead to the neurodegenerative disorder chorea …