Malaria and leishmaniasis: Updates on co-infection

U Ornellas-Garcia, P Cuervo… - Frontiers in …, 2023 - frontiersin.org
Malaria and leishmaniasis are endemic parasitic diseases in tropical and subtropical
countries. Although the overlap of these diseases in the same host is frequently described …

Insights into the drug screening approaches in leishmaniasis

B Gopu, P Kour, R Pandian, K Singh - International Immunopharmacology, 2023 - Elsevier
Leishmaniasis, a tropically neglected disease, is responsible for the high mortality and
morbidity ratio in poverty-stricken areas. Currently, no vaccine is available for the complete …

Nitro compounds against trypanosomatidae parasites: Heroes or villains?

PF da Silva Santos-Júnior, LR Silva… - Bioorganic & Medicinal …, 2022 - Elsevier
Abstract Chagas disease and Human African trypanosomiasis (HAT) are caused by
Trypanosoma cruzi, T. brucei rhodesiense or T. b. gambiense parasites, respectively; while …

Seroprevalence of canine leishmaniosis in asymptomatic dogs in Kosovo

B Xhekaj, J Stefanovska, K Sherifi, A Rexhepi… - Parasitology …, 2023 - Springer
Canine leishmaniosis (CanL) is a neglected zoonotic disease caused by Leishmania spp.
Leishmania infantum is the species responsible for the zoonotic form of the disease where …

[HTML][HTML] Exploring the impact of epidemiological and clinical factors on the progression of canine leishmaniosis by statistical and whole genome analyses: from breed …

CR Sanz, J Sarquis, MÁ Daza, G Miró - International Journal for …, 2024 - Elsevier
Canine leishmaniosis (CanL), caused by Leishmania infantum, is a complex disease of
growing importance in Europe. Clinical manifestations result from the down-modulation of …

Clinical polymorphism of zoonotic cutaneous leishmaniasis: combination of the clinical and the parasitological diagnosis

S Layouni, L Remadi, A Kidar… - Parasitology …, 2024 - Springer
Zoonotic cutaneous leishmaniasis (ZCL) is a neglected tropical disease caused by
Leishmania (L.) major. This zoonosis is characterized by a broad-spectrum clinical …

[HTML][HTML] Overexpression of iron super oxide dismutases A/B genes are associated with antimony resistance of Leishmania tropica clinical isolates

A Bahrami, M Mohebali, HR Nafchi… - Iranian Journal of …, 2022 - ncbi.nlm.nih.gov
Background: Pentavalent antimonial has been a drug of choice against leishmaniasis,
despite the emergence of treatment failure. Identification of resistance markers is urgently …

Leishmania major strain-dependent macrophage activation contributes to pathogenicity in the absence of lymphocytes

J Alshaweesh, R Nakamura, Y Tanaka… - Microbiology …, 2022 - Am Soc Microbiol
Infection of C57BL/6 wild-type mice with Leishmania major 5-ASKH or Friedlin strains results
in relatively similar pathogenicity with self-healing lesions within weeks. Parasite clearance …

Cytokines signatures and susceptibility to cutaneous leishmaniasis in patients from Sistan and Baluchestan province of Iran

S Jahanshahi, HR Nejad, B Kazemi, P Saeedi - Gene, 2024 - Elsevier
Background Cutaneous leishmaniasis (CL) is a complex, multifactorial disease that results
from environmental factors such as parasite polymorphism, phlebotomine vectors, and host …

Genetic diversity in Leishmania infantum and Leishmania tropica isolates from human and canine hosts in northern Morocco

M Hakkour, B Badaoui, SEH Khatat, H Sahibi, H Fellah… - Gene, 2024 - Elsevier
This study investigated nine provinces in northern Morocco and collected 275 skin scraping,
22 bone marrow aspirates, and 89 fine needle aspirations from suspected cutaneous …