Drug repurposing for viral cancers: a paradigm of machine learning, deep learning, and virtual screening‐based approaches
Cancer management is major concern of health organizations and viral cancers account for
approximately 15.4% of all known human cancers. Due to large number of patients, efficient …
approximately 15.4% of all known human cancers. Due to large number of patients, efficient …
Both full-length and protease-cleaved products of osteopontin are elevated in infectious diseases
T Hattori, H Iwasaki-Hozumi, G Bai, H Chagan-Yasutan… - Biomedicines, 2021 - mdpi.com
Circulating full-length osteopontin (FL-OPN) is elevated in plasma from patients with various
infectious diseases, such as adult T-cell leukemia, Mycobacterium tuberculosis (TB) …
infectious diseases, such as adult T-cell leukemia, Mycobacterium tuberculosis (TB) …
Role of miRNAs in human T cell leukemia virus type 1 induced T cell leukemia: a literature review and bioinformatics approach
CB Machado, LS da Cunha, JHS Maués… - International Journal of …, 2022 - mdpi.com
Human T cell leukemia virus type 1 (HTLV-1) was identified as the first pathogenic human
retrovirus and is estimated to infect 5 to 10 million individuals worldwide. Unlike other …
retrovirus and is estimated to infect 5 to 10 million individuals worldwide. Unlike other …
Gut microbiota: role and association with tumorigenesis in different malignancies
A Ali, A Ara, MK Kashyap - Molecular Biology Reports, 2022 - Springer
The microbiota has been associated with different cancer and may vary from patient to
patient. A specific microbial strain can alter the progression of cancer and therapeutic …
patient. A specific microbial strain can alter the progression of cancer and therapeutic …
Exploring the impact of hydrogen sulfide on hematologic malignancies: A review
S Lou, ZL Jiang, YW Zhu, RY Zhang, Y Wang, T Chu… - Cellular …, 2024 - Elsevier
Hydrogen sulfide (H 2 S) is one of the three most crucial gaseous messengers in the body.
The discovery of H 2 S donors, coupled with its endogenous synthesis capability, has …
The discovery of H 2 S donors, coupled with its endogenous synthesis capability, has …
[HTML][HTML] Autophagy modulation by viral infections influences tumor development
Autophagy is a self-degradative process important for balancing cellular homeostasis at
critical times in development and/or in response to nutrient stress. This is particularly …
critical times in development and/or in response to nutrient stress. This is particularly …
Anticancer potential of isovanillin-based symmetrical azine: Synthesis, structure, molecular modeling, in silico leukemia inhibition and MD simulation
K Fadli, A Bouchama, A Tabbiche, C Chiter… - Journal of Molecular …, 2024 - Elsevier
Isovanillin azine, a symmetrical azine easily synthesized by reaction of 3-hydroxy-4-
methoxybenzaldehyde (isovanillin) with hydrazine hydrate, was identified as a potential …
methoxybenzaldehyde (isovanillin) with hydrazine hydrate, was identified as a potential …
[HTML][HTML] Basic zipper protein (HBZ): biomarcador diagnóstico y de seguimiento de leucemia/linfoma T del adulto
V Riaño Ibáñez, DA Villamil Rodríguez… - Revista Cubana de …, 2023 - scielo.sld.cu
Objetivo: Presentar la proteína basic zipper protein como marcador diagnóstico y de
seguimiento al tratamiento de la leucemia-linfoma de células T. Métodos: Se consultó …
seguimiento al tratamiento de la leucemia-linfoma de células T. Métodos: Se consultó …
Hydrogen sulfide inhibits human T‐cell leukemia virus type‐1 (HTLV‐1) protein expression via regulation of ATG4B
H Liu, J Sun, X Cheng, L Duan, S Guo… - Journal of Medical …, 2023 - Wiley Online Library
Hydrogen sulfide (H2S) is a redox gasotransmitter. It has been shown that H2S has a key
role in host antiviral defense by inhibiting interleukin production and S‐sulfhydrating Keap1 …
role in host antiviral defense by inhibiting interleukin production and S‐sulfhydrating Keap1 …
[PDF][PDF] An Overview of the Unfolded Protein Response (UPR) and Autophagy Pathways in Human Viral Oncogenesis
Abstract Autophagy and Unfolded Protein Response (UPR) can be regarded as the safe
keepers of cells exposed to intense stress. Autophagy maintains cellular homeostasis …
keepers of cells exposed to intense stress. Autophagy maintains cellular homeostasis …