Drug repurposing for viral cancers: a paradigm of machine learning, deep learning, and virtual screening‐based approaches

F Ahmed, IS Kang, KH Kim, A Asif… - Journal of Medical …, 2023 - Wiley Online Library
Cancer management is major concern of health organizations and viral cancers account for
approximately 15.4% of all known human cancers. Due to large number of patients, efficient …

Both full-length and protease-cleaved products of osteopontin are elevated in infectious diseases

T Hattori, H Iwasaki-Hozumi, G Bai, H Chagan-Yasutan… - Biomedicines, 2021 - mdpi.com
Circulating full-length osteopontin (FL-OPN) is elevated in plasma from patients with various
infectious diseases, such as adult T-cell leukemia, Mycobacterium tuberculosis (TB) …

Role of miRNAs in human T cell leukemia virus type 1 induced T cell leukemia: a literature review and bioinformatics approach

CB Machado, LS da Cunha, JHS Maués… - International Journal of …, 2022 - mdpi.com
Human T cell leukemia virus type 1 (HTLV-1) was identified as the first pathogenic human
retrovirus and is estimated to infect 5 to 10 million individuals worldwide. Unlike other …

Gut microbiota: role and association with tumorigenesis in different malignancies

A Ali, A Ara, MK Kashyap - Molecular Biology Reports, 2022 - Springer
The microbiota has been associated with different cancer and may vary from patient to
patient. A specific microbial strain can alter the progression of cancer and therapeutic …

Exploring the impact of hydrogen sulfide on hematologic malignancies: A review

S Lou, ZL Jiang, YW Zhu, RY Zhang, Y Wang, T Chu… - Cellular …, 2024 - Elsevier
Hydrogen sulfide (H 2 S) is one of the three most crucial gaseous messengers in the body.
The discovery of H 2 S donors, coupled with its endogenous synthesis capability, has …

[HTML][HTML] Autophagy modulation by viral infections influences tumor development

L Leonardi, S Sibéril, M Alifano, I Cremer… - Frontiers in …, 2021 - frontiersin.org
Autophagy is a self-degradative process important for balancing cellular homeostasis at
critical times in development and/or in response to nutrient stress. This is particularly …

Anticancer potential of isovanillin-based symmetrical azine: Synthesis, structure, molecular modeling, in silico leukemia inhibition and MD simulation

K Fadli, A Bouchama, A Tabbiche, C Chiter… - Journal of Molecular …, 2024 - Elsevier
Isovanillin azine, a symmetrical azine easily synthesized by reaction of 3-hydroxy-4-
methoxybenzaldehyde (isovanillin) with hydrazine hydrate, was identified as a potential …

[HTML][HTML] Basic zipper protein (HBZ): biomarcador diagnóstico y de seguimiento de leucemia/linfoma T del adulto

V Riaño Ibáñez, DA Villamil Rodríguez… - Revista Cubana de …, 2023 - scielo.sld.cu
Objetivo: Presentar la proteína basic zipper protein como marcador diagnóstico y de
seguimiento al tratamiento de la leucemia-linfoma de células T. Métodos: Se consultó …

Hydrogen sulfide inhibits human T‐cell leukemia virus type‐1 (HTLV‐1) protein expression via regulation of ATG4B

H Liu, J Sun, X Cheng, L Duan, S Guo… - Journal of Medical …, 2023 - Wiley Online Library
Hydrogen sulfide (H2S) is a redox gasotransmitter. It has been shown that H2S has a key
role in host antiviral defense by inhibiting interleukin production and S‐sulfhydrating Keap1 …

[PDF][PDF] An Overview of the Unfolded Protein Response (UPR) and Autophagy Pathways in Human Viral Oncogenesis

S Dutta, A Ganguly, SG Roy - 2024 - researchgate.net
Abstract Autophagy and Unfolded Protein Response (UPR) can be regarded as the safe
keepers of cells exposed to intense stress. Autophagy maintains cellular homeostasis …