Human endogenous retroviruses (HERVs) are relics of ancient infections accounting for
about the 8% of our genome. Despite their persistence in human DNA led to the …

In primary Sjögren syndrome (pSS), chronic inflammation of exocrine glands results in tissue
destruction and sicca symptoms, primarily of the mouth and eyes. Fatigue, arthralgia and …

Methylation analysis of circulating cell-free DNA (cirDNA), as a liquid biopsy, has a
significant potential to advance the detection, prognosis, and treatment of cancer, as well as …

DNA methylation is a prevalent epigenetic modification involved in regulating a number of
essential cellular processes, including genomic accessibility and transcriptional outcomes …

Human Endogenous Retroviruses (HERVs) are ancient infection relics constituting~ 8% of
our DNA. While HERVs' genomic characterization is still ongoing, impressive amounts of …

ANCA-associated vasculitis is an autoimmune condition characterized by vascular
inflammation and organ damage. Pharmacologically induced remission of this condition is …

Epigenetics refers to a set of regulatory mechanisms that affect gene expression, while the
original sequence of the DNA remains unchanged. Because the advance of noncoding …

The epigenome may be an important interface between exposure to environmental
contaminants and adverse outcome on human health. Many environmental pollutants …

Purpose: DNA methylation is a key epigenetic modification involved in various biological
processes and diseases. Corneal epithelial wound healing (CEWH) is essential for restoring …

We investigated the DNA damage response and repair network in 18 patients with active
rheumatoid arthritis and tested the hypothesis that treatment influences this network. A 3-fold …